Susana Priego-Jiménez , Maribel Lucerón-Lucas-Torres , Marta Carolina Ruiz-Grao , Mª José Guzmán-Pavón , Patricia Lorenzo-García , Felipe Araya-Quintanilla , Celia Álvarez-Bueno
{"title":"运动干预对慢性阻塞性肺病患者摄氧量的影响：随机对照试验的网络荟萃分析。","authors":"Susana Priego-Jiménez , Maribel Lucerón-Lucas-Torres , Marta Carolina Ruiz-Grao , Mª José Guzmán-Pavón , Patricia Lorenzo-García , Felipe Araya-Quintanilla , Celia Álvarez-Bueno","doi":"10.1016/j.rehab.2024.101875","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Although aerobic training leads to physiological improvements in people with chronic obstructive pulmonary disease (COPD), measured by the VO2 peak, there is no evidence as to which type of physical exercise intervention is the most effective in improving the VO<sub>2</sub> peak or max.</div></div><div><h3>Objective</h3><div>A network meta-analysis (NMA) was performed to determine the effects of different physical interventions on oxygen uptake in people with COPD.</div></div><div><h3>Methods</h3><div>A literature search was performed from database inception to February 2024. Randomized controlled trials on the effectiveness of exercise programs on oxygen uptake with COPD were included. We assessed the risk of bias using the Cochrane Risk of Bias (RoB 2.0) tool and the quality of the evidence using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) tool. Pairwise meta-analyses and NMAs were performed for direct and indirect evidence.</div></div><div><h3>Results</h3><div>A total of 22 studies were included in this NMA. The highest effects for improvement in oxygen uptake scores were for continuous, moderate-intensity endurance exercise versus a control (effect size [ES]: 1.17; 95% CI 0.59 to 1.74), followed by continuous, high-intensity endurance exercise versus a control (ES: 0.47; 95% CI 0.08 to 0.85), and combined exercise versus a control (ES: 0.41; 95% CI 0.18 to 0.64).</div></div><div><h3>Conclusions</h3><div>Continuous, moderate-intensity endurance exercise should be considered the most effective strategy to improve oxygen uptake in people with COPD, followed by continuous, high-intensity endurance exercise and combined exercise. Due to the importance of VO<sub>2</sub> as a predictor of quality of life and mortality in people with COPD, it is essential to include its assessment in clinical guidelines and to include the most effective physical activity interventions to improve it.</div></div><div><h3>Trial Registration</h3><div>PROSPERO database: CRD42023425893</div></div>","PeriodicalId":56030,"journal":{"name":"Annals of Physical and Rehabilitation Medicine","volume":"67 8","pages":"Article 101875"},"PeriodicalIF":3.9000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of exercise interventions on oxygen uptake in people with chronic obstructive pulmonary disease: A network meta-analysis of randomized controlled trials\",\"authors\":\"Susana Priego-Jiménez , Maribel Lucerón-Lucas-Torres , Marta Carolina Ruiz-Grao , Mª José Guzmán-Pavón , Patricia Lorenzo-García , Felipe Araya-Quintanilla , Celia Álvarez-Bueno\",\"doi\":\"10.1016/j.rehab.2024.101875\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Although aerobic training leads to physiological improvements in people with chronic obstructive pulmonary disease (COPD), measured by the VO2 peak, there is no evidence as to which type of physical exercise intervention is the most effective in improving the VO<sub>2</sub> peak or max.</div></div><div><h3>Objective</h3><div>A network meta-analysis (NMA) was performed to determine the effects of different physical interventions on oxygen uptake in people with COPD.</div></div><div><h3>Methods</h3><div>A literature search was performed from database inception to February 2024. Randomized controlled trials on the effectiveness of exercise programs on oxygen uptake with COPD were included. We assessed the risk of bias using the Cochrane Risk of Bias (RoB 2.0) tool and the quality of the evidence using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) tool. Pairwise meta-analyses and NMAs were performed for direct and indirect evidence.</div></div><div><h3>Results</h3><div>A total of 22 studies were included in this NMA. The highest effects for improvement in oxygen uptake scores were for continuous, moderate-intensity endurance exercise versus a control (effect size [ES]: 1.17; 95% CI 0.59 to 1.74), followed by continuous, high-intensity endurance exercise versus a control (ES: 0.47; 95% CI 0.08 to 0.85), and combined exercise versus a control (ES: 0.41; 95% CI 0.18 to 0.64).</div></div><div><h3>Conclusions</h3><div>Continuous, moderate-intensity endurance exercise should be considered the most effective strategy to improve oxygen uptake in people with COPD, followed by continuous, high-intensity endurance exercise and combined exercise. Due to the importance of VO<sub>2</sub> as a predictor of quality of life and mortality in people with COPD, it is essential to include its assessment in clinical guidelines and to include the most effective physical activity interventions to improve it.</div></div><div><h3>Trial Registration</h3><div>PROSPERO database: CRD42023425893</div></div>\",\"PeriodicalId\":56030,\"journal\":{\"name\":\"Annals of Physical and Rehabilitation Medicine\",\"volume\":\"67 8\",\"pages\":\"Article 101875\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Physical and Rehabilitation Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1877065724000599\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"REHABILITATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Physical and Rehabilitation Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1877065724000599","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"REHABILITATION","Score":null,"Total":0}
引用次数: 0
摘要
背景：虽然有氧训练能改善慢性阻塞性肺病（COPD）患者的生理状况（以VO2峰值衡量），但没有证据表明哪种体育锻炼干预对提高VO2峰值或最大值最有效：目的：进行了一项网络荟萃分析（NMA），以确定不同体育干预措施对慢性阻塞性肺病患者摄氧量的影响：方法：对从数据库开始到 2024 年 2 月的文献进行了检索。方法：从数据库开始到 2024 年 2 月，我们对文献进行了检索，纳入了有关运动项目对慢性阻塞性肺病患者摄氧量效果的随机对照试验。我们使用科克伦偏倚风险（RoB 2.0）工具评估了偏倚风险，并使用建议、评估、发展和评价分级（GRADE）工具评估了证据质量。对直接和间接证据进行了配对荟萃分析和近似荟萃分析：结果：共有 22 项研究被纳入 NMA。持续、中等强度的耐力运动与对照组相比，摄氧量评分的改善效果最高（效应大小 [ES]：1.17；95% CI 0.59 至 1.74），其次是持续、高强度的耐力运动与对照组相比（ES：0.47；95% CI 0.08 至 0.85），以及综合运动与对照组相比（ES：0.41；95% CI 0.18 至 0.64）：结论：持续、中等强度的耐力运动应被视为改善慢性阻塞性肺病患者摄氧量的最有效策略，其次是持续、高强度的耐力运动和综合运动。由于容氧量是预测慢性阻塞性肺病患者生活质量和死亡率的重要指标，因此必须将其评估纳入临床指南，并采用最有效的体育锻炼干预措施来提高容氧量：试验注册：PROSPERO 数据库：试验注册：PROSPERO 数据库：CRD42023425893。
Effect of exercise interventions on oxygen uptake in people with chronic obstructive pulmonary disease: A network meta-analysis of randomized controlled trials
Background
Although aerobic training leads to physiological improvements in people with chronic obstructive pulmonary disease (COPD), measured by the VO2 peak, there is no evidence as to which type of physical exercise intervention is the most effective in improving the VO2 peak or max.
Objective
A network meta-analysis (NMA) was performed to determine the effects of different physical interventions on oxygen uptake in people with COPD.
Methods
A literature search was performed from database inception to February 2024. Randomized controlled trials on the effectiveness of exercise programs on oxygen uptake with COPD were included. We assessed the risk of bias using the Cochrane Risk of Bias (RoB 2.0) tool and the quality of the evidence using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) tool. Pairwise meta-analyses and NMAs were performed for direct and indirect evidence.
Results
A total of 22 studies were included in this NMA. The highest effects for improvement in oxygen uptake scores were for continuous, moderate-intensity endurance exercise versus a control (effect size [ES]: 1.17; 95% CI 0.59 to 1.74), followed by continuous, high-intensity endurance exercise versus a control (ES: 0.47; 95% CI 0.08 to 0.85), and combined exercise versus a control (ES: 0.41; 95% CI 0.18 to 0.64).
Conclusions
Continuous, moderate-intensity endurance exercise should be considered the most effective strategy to improve oxygen uptake in people with COPD, followed by continuous, high-intensity endurance exercise and combined exercise. Due to the importance of VO2 as a predictor of quality of life and mortality in people with COPD, it is essential to include its assessment in clinical guidelines and to include the most effective physical activity interventions to improve it.
期刊介绍：
Annals of Physical and Rehabilitation Medicine covers all areas of Rehabilitation and Physical Medicine; such as: methods of evaluation of motor, sensory, cognitive and visceral impairments; acute and chronic musculoskeletal disorders and pain; disabilities in adult and children ; processes of rehabilitation in orthopaedic, rhumatological, neurological, cardiovascular, pulmonary and urological diseases.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
