一名腹膜透析患者的淀粉样棒状杆菌腹膜炎:病例报告和文献综述。

Access microbiology Pub Date : 2024-10-30 eCollection Date: 2024-01-01 DOI:10.1099/acmi.0.000880.v3
Fatima Zahra Adil, Imane Aragon, Elmostafa Benaissa, Yassine Ben Lahlou, Fatna Bssaibis, Adil Maleb, Mariama Chadli, Mostafa Elouennass
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引用次数: 0

摘要

腹膜透析是一种基于腹膜过滤功能的血液净化技术,用于治疗终末期慢性肾衰竭。感染通常是由于导管操作过程中无菌操作不当引起的,一般由表皮葡萄球菌和金黄色葡萄球菌引起。通常被认为不具致病性的棒状杆菌很少参与这些感染。我们报告了一例正在接受腹膜透析的患者因淀粉样棒状杆菌引起的腹膜炎。诊断是根据透析液的细胞细菌学检查做出的,透析液中两次出现高浓度白细胞,其中以中性多形核为主,琼脂培养基上的菌落呈单形。患者成功接受了万古霉素治疗,症状得到缓解,透析液也得到消毒。虽然罕见,但棒状杆菌的参与强调了确认其致病性的重要性。要更好地了解这些感染的流行病学并指导未来的治疗,还需要进一步的研究。本病例还突出表明,尽管传统上把棒状杆菌归类为污染物,但仍需要采用严格的方法来确认其致病性。
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Corynebacterium amycolatum peritonitis in a patient undergoing peritoneal dialysis: case report and literature review.

Peritoneal dialysis is a blood purification technique used in cases of end-stage chronic kidney failure, based on the filtering capabilities of the peritoneum. Infections, often caused by poor asepsis during catheter manipulation, are generally attributed to Staphylococcus epidermidis and Staphylococcus aureus. Corynebacterium, usually considered non-pathogenic, is rarely involved in these infections. We present a case of peritonitis due to Corynebacterium amycolatum in a patient undergoing peritoneal dialysis. The diagnosis was made based on cytobacteriological examination of the dialysate fluid, which on two occasions showed high levels of white blood cells with a predominance of neutrophilic polymorphonuclear and a monomorphic appearance of colonies on agar medium, whose identification by biochemical tests and antibiotic sensitivity study confirmed the presence of C. amycolatum. The patient was successfully treated with vancomycin, resulting in symptom resolution and sterilization of the dialysate fluid. Although rare, the involvement of Corynebacterium species underscores the importance of confirming its pathogenicity. Further studies are needed to better understand the epidemiology of these infections and guide future treatments. This case also highlights the need for a rigorous approach to confirming the pathogenicity of Corynebacterium despite its traditional classification as a contaminant.

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