时间和州阿片类药物立法减少了选择性肩部手术中的阿片类药物填充。

Daniel J Cunningham, Jay Levin, Jeffrey O'Donnell, Joshua Helmkamp, Oke Anakwenze, Tally Lassiter, Mark J Gage, Christopher S Klifto
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引用次数: 0

摘要

为应对阿片类药物在美国的流行,美国颁布了限制阿片类药物的法律。然而,这项立法对肩部择期手术围手术期阿片类药物处方的影响还不甚了解。这是一项观察性研究,利用国家保险数据库(n = 231,634 名患者)对 2010 年至 2019 年期间接受肩部手术的患者 90 天围手术期阿片类药物处方的填写情况进行回顾。统计评估了年份和阿片类药物限制法规对首次处方和 90 天阿片类药物累积用量的影响。从 2010 年到 2019 年,阿片类药物的首次处方量和累计处方量均大幅下降(首次 5 毫克羟考酮当量从 49 降至 44.4,累计 5 毫克羟考酮当量从 132.8 降至 72.3;所有 p <0.001)。有阿片类药物限制立法的州在相似的时间范围内阿片类药物初始处方量和累计处方量的减少幅度更大(p < 0.001)。随着时间的推移和各州立法的实施,肩部手术围手术期阿片类药物处方量明显减少。个人处方者以及州和国家立法者应继续寻求减少阿片类药物过量处方的方法。(外科骨科进展杂志》33(3):152-157,2024 年)。
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Time and State Opioid Legislation Have Reduced Opioid Filling in Elective Shoulder Surgery.

Opioid-limiting legislation has been enacted in response to the opioid epidemic in the United States. However, the impact of this legislation on perioperative opioid prescribing in elective shoulder surgery is not well understood. This is an observational review of 90-day perioperative opioid-prescription filling by patients undergoing shoulder surgery using a national insurance database (n = 231,634 patients) between 2010 and 2019. Statistics evaluated the impact of the year and opioid-limiting legislation on first prescription and cumulative 90-day opioid filling. Initial and cumulative opioid-prescription volume decreased significantly from 2010 to 2019 (49 to 44.4 initial oxycodone 5-mg equivalents, 132.8 to 72.3 cumulative oxycodone 5-mg equivalents; all p < 0.001). States with opioid-limiting legislation had larger reductions in initial and cumulative opioid-prescription filling over similar time frames (p < 0.001). Perioperative opioid prescribing has decreased significantly in shoulder surgery with time and state legislation. Individual prescribers and state and national legislators should continue to seek ways to reduce opioid overprescribing. (Journal of Surgical Orthopaedic Advances 33(3):152-157, 2024).

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