Blerina Resuli MD , Diego Kauffmann-Guerrero MD , Jürgen Behr MD , Amanda Tufman MD
{"title":"表皮生长因子受体突变 NSCLC 中同时出现 HER2 突变：病例报告","authors":"Blerina Resuli MD , Diego Kauffmann-Guerrero MD , Jürgen Behr MD , Amanda Tufman MD","doi":"10.1016/j.jtocrr.2024.100719","DOIUrl":null,"url":null,"abstract":"<div><div><em>HER2</em> mutation and amplification have been identified as distinct molecular targets in lung cancer with different therapeutic and prognostic values. The coexistence of <em>HER2</em> and <em>EGFR</em> mutations is extremely rare, and therefore, no data exist on the best treatment in these cases.</div></div>","PeriodicalId":17675,"journal":{"name":"JTO Clinical and Research Reports","volume":"5 12","pages":"Article 100719"},"PeriodicalIF":3.0000,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Simultaneous Occurrence of HER2 Mutations in EGFR Mutant NSCLC: Case Reports\",\"authors\":\"Blerina Resuli MD , Diego Kauffmann-Guerrero MD , Jürgen Behr MD , Amanda Tufman MD\",\"doi\":\"10.1016/j.jtocrr.2024.100719\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><em>HER2</em> mutation and amplification have been identified as distinct molecular targets in lung cancer with different therapeutic and prognostic values. The coexistence of <em>HER2</em> and <em>EGFR</em> mutations is extremely rare, and therefore, no data exist on the best treatment in these cases.</div></div>\",\"PeriodicalId\":17675,\"journal\":{\"name\":\"JTO Clinical and Research Reports\",\"volume\":\"5 12\",\"pages\":\"Article 100719\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-09-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JTO Clinical and Research Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666364324000894\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JTO Clinical and Research Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666364324000894","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Simultaneous Occurrence of HER2 Mutations in EGFR Mutant NSCLC: Case Reports
HER2 mutation and amplification have been identified as distinct molecular targets in lung cancer with different therapeutic and prognostic values. The coexistence of HER2 and EGFR mutations is extremely rare, and therefore, no data exist on the best treatment in these cases.
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