Muhammad Usama , Musammir Khan , Xingzhou Peng , Junjie Wang
{"title":"基于壳聚糖/氧化石墨烯的生物复合动态薄膜在无酶生物传感中的应用","authors":"Muhammad Usama , Musammir Khan , Xingzhou Peng , Junjie Wang","doi":"10.1016/j.mseb.2024.117766","DOIUrl":null,"url":null,"abstract":"<div><div>Biocomposite films of chitosan (CS) and graphene oxide (GO) filler using glutaraldehyde crosslinker was prepared by Schiff-base linkages for enzyme-free biosensing applications. The obtained biocomposites (CS/GO) was characterized by different physicochemical techniques. The glassy carbon electrode (GCE) modified with these biocomposites indicated enhanced redox peak currents and peak separation potentials, as well as accompanied by a reduction in electron transfer resistance as compared with pristine CS material. The CS/GO modified GCE was tested for biosensing in the linear concentration range of glucose (Gl) ∼ 1.25 to 125 ppm, gallic acid (GA) ∼ 6.25 to 75 ppm and dopamine (DA) ∼ 25 to 100 ppm. Moreover, the biosensor indicated high sensitivity (72.9 µA.mM<sup>−1</sup>.cm<sup>−2</sup>), lower detection limit (0.094 mM) and lower quantification limit (0.313 mM) against Gl as compared with previous reported values. The proposed electro-oxidation mechanism on the modified GCE surface indicated the biocomposites as promising green electroactive smart materials for enzyme-free biosensing applications.</div></div>","PeriodicalId":18233,"journal":{"name":"Materials Science and Engineering B-advanced Functional Solid-state Materials","volume":"310 ","pages":"Article 117766"},"PeriodicalIF":3.9000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chitosan/graphene oxide based biocomposite dynamic films for enzyme-free biosensing application\",\"authors\":\"Muhammad Usama , Musammir Khan , Xingzhou Peng , Junjie Wang\",\"doi\":\"10.1016/j.mseb.2024.117766\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Biocomposite films of chitosan (CS) and graphene oxide (GO) filler using glutaraldehyde crosslinker was prepared by Schiff-base linkages for enzyme-free biosensing applications. The obtained biocomposites (CS/GO) was characterized by different physicochemical techniques. The glassy carbon electrode (GCE) modified with these biocomposites indicated enhanced redox peak currents and peak separation potentials, as well as accompanied by a reduction in electron transfer resistance as compared with pristine CS material. The CS/GO modified GCE was tested for biosensing in the linear concentration range of glucose (Gl) ∼ 1.25 to 125 ppm, gallic acid (GA) ∼ 6.25 to 75 ppm and dopamine (DA) ∼ 25 to 100 ppm. Moreover, the biosensor indicated high sensitivity (72.9 µA.mM<sup>−1</sup>.cm<sup>−2</sup>), lower detection limit (0.094 mM) and lower quantification limit (0.313 mM) against Gl as compared with previous reported values. The proposed electro-oxidation mechanism on the modified GCE surface indicated the biocomposites as promising green electroactive smart materials for enzyme-free biosensing applications.</div></div>\",\"PeriodicalId\":18233,\"journal\":{\"name\":\"Materials Science and Engineering B-advanced Functional Solid-state Materials\",\"volume\":\"310 \",\"pages\":\"Article 117766\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2024-10-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Materials Science and Engineering B-advanced Functional Solid-state Materials\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0921510724005956\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Science and Engineering B-advanced Functional Solid-state Materials","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0921510724005956","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Chitosan/graphene oxide based biocomposite dynamic films for enzyme-free biosensing application
Biocomposite films of chitosan (CS) and graphene oxide (GO) filler using glutaraldehyde crosslinker was prepared by Schiff-base linkages for enzyme-free biosensing applications. The obtained biocomposites (CS/GO) was characterized by different physicochemical techniques. The glassy carbon electrode (GCE) modified with these biocomposites indicated enhanced redox peak currents and peak separation potentials, as well as accompanied by a reduction in electron transfer resistance as compared with pristine CS material. The CS/GO modified GCE was tested for biosensing in the linear concentration range of glucose (Gl) ∼ 1.25 to 125 ppm, gallic acid (GA) ∼ 6.25 to 75 ppm and dopamine (DA) ∼ 25 to 100 ppm. Moreover, the biosensor indicated high sensitivity (72.9 µA.mM−1.cm−2), lower detection limit (0.094 mM) and lower quantification limit (0.313 mM) against Gl as compared with previous reported values. The proposed electro-oxidation mechanism on the modified GCE surface indicated the biocomposites as promising green electroactive smart materials for enzyme-free biosensing applications.
期刊介绍：
The journal provides an international medium for the publication of theoretical and experimental studies and reviews related to the electronic, electrochemical, ionic, magnetic, optical, and biosensing properties of solid state materials in bulk, thin film and particulate forms. Papers dealing with synthesis, processing, characterization, structure, physical properties and computational aspects of nano-crystalline, crystalline, amorphous and glassy forms of ceramics, semiconductors, layered insertion compounds, low-dimensional compounds and systems, fast-ion conductors, polymers and dielectrics are viewed as suitable for publication. Articles focused on nano-structured aspects of these advanced solid-state materials will also be considered suitable.
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