内在调控机制保护人类皮肤肥大细胞免受 MRGPRX2 的过度激活--LAD2 细胞中 MRGPRX2 的缺乏导致了肥大细胞系的高反应性。

{"title":"内在调控机制保护人类皮肤肥大细胞免受 MRGPRX2 的过度激活--LAD2 细胞中 MRGPRX2 的缺乏导致了肥大细胞系的高反应性。","authors":"Zhuoran Li , Jean Schneikert , Gürkan Bal , Manqiu Jin , Kristin Franke , Torsten Zuberbier , Magda Babina","doi":"10.1016/j.jid.2024.10.593","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":16311,"journal":{"name":"Journal of Investigative Dermatology","volume":"145 5","pages":"Pages 1215-1219.e4"},"PeriodicalIF":5.7000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Intrinsic Regulatory Mechanisms Protect Human Skin Mast Cells from Excessive MRGPRX2 Activation: Paucity in LAD2 (Laboratory of Allergic Diseases 2) Cells Contributes to Hyperresponsiveness of the Mast Cell Line\",\"authors\":\"Zhuoran Li , Jean Schneikert , Gürkan Bal , Manqiu Jin , Kristin Franke , Torsten Zuberbier , Magda Babina\",\"doi\":\"10.1016/j.jid.2024.10.593\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":16311,\"journal\":{\"name\":\"Journal of Investigative Dermatology\",\"volume\":\"145 5\",\"pages\":\"Pages 1215-1219.e4\"},\"PeriodicalIF\":5.7000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Investigative Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0022202X24028756\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/10/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Investigative Dermatology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022202X24028756","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/30 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}