老年长期住院病人的便秘:氢氧化镁和大剂量泻药的治疗。

Annals of clinical research Pub Date : 1987-01-01
O Kinnunen, J Salokannel
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引用次数: 0

摘要

64名年龄在65岁或以上的老年长期住院患者参加了这项试验。所有人在研究前都在使用泻药。对于研究中的泻药,氢氧化镁的平均剂量为25毫升/天,散装泻药为8.7克/天。与散装泻药相比,氢氧化镁引起更频繁的排便习惯(13.2周vs. 10.4/4周,p < 0.001),并且不需要像散装泻药那样经常添加泻药bisacodyl(2.3周vs. 3.3/4周,p < 0.01)。在氢氧化镁治疗期间,大便稠度也更为正常。2例患者经氢氧化镁治疗后血清镁均超过1.25 mmol/l,但未出现高镁血症的临床症状。我们的研究表明氢氧化镁在治疗老年长期住院患者便秘方面比大剂量泻药更有效。
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Constipation in elderly long-stay patients: its treatment by magnesium hydroxide and bulk-laxative.

Sixty-four geriatric long-stay patients aged 65 years or older participated in the trial. All were using laxatives prior to the study. For the study laxatives the mean dose of magnesium hydroxide was 25 ml daily and for bulk-laxative 8.7 g daily. Magnesium hydroxide caused a more frequent bowel habit (13.2 vs. 10.4/4 weeks, p less than 0.001) than bulk-laxative and additional laxative bisacodyl was not needed as often as with bulk-laxative (2.3 vs. 3.3/4 weeks, p less than 0.01). Also the stool consistency was more normal during the magnesium hydroxide treatment. In two patients serum magnesium was over 1.25 mmol/l after the magnesium hydroxide treatment but there were no clinical signs of hypermagnaesemia. Our study indicated magnesium hydroxide to be more efficient than bulk-laxative in treating constipation in elderly long-stay patients.

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