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引用次数: 0
摘要
本病例是一名 4 个月大的川崎病患者,在疾病复发后出现冠状动脉病变。根据 "评估免疫球蛋白加类固醇疗效的随机对照试验 "的指导方针,患者的症状最初有所改善。然而,尽管 C 反应蛋白水平很低,但病情还是复发了,导致冠状动脉明显增生。使用第三剂静脉注射免疫球蛋白和环孢素治疗后,冠状动脉畸形慢慢缩小。本病例凸显了仅通过临床症状和 C 反应蛋白水平来监测川崎病进展的困难。我们还强调了对接受类固醇等抗炎治疗的患者进行超声心动图监测的必要性,因为冠状动脉问题可能在没有川崎病通常症状或 C 反应蛋白水平升高的情况下出现或持续。
An infant case of coronary artery aneurysms with no systemic symptoms after treatment for Kawasaki disease.
This case is a 4-month-old patient with Kawasaki disease who showed coronary artery lesions after a disease relapse. Following the guidelines from the Randomised Controlled Trial to Assess Immunoglobulin plus Steroid Efficacy, the patient initially saw an improvement in symptoms. However, a relapse occurred despite low levels of C-reactive protein, leading to significant coronary artery growth. Treatment with a third dose of intravenous immunoglobulin and cyclosporine led to a slow reduction in the size of the coronary artery abnormalities. This case highlights the difficulty in monitoring Kawasaki disease progression through clinical symptoms and C-reactive protein levels alone. We also emphasise the necessity of echocardiographic monitoring in patients receiving anti-inflammatory treatments, including steroids, because coronary artery problems can arise or continue without the usual signs of Kawasaki disease or increased C-reactive protein levels.
期刊介绍:
Cardiology in the Young is devoted to cardiovascular issues affecting the young, and the older patient suffering the sequels of congenital heart disease, or other cardiac diseases acquired in childhood. The journal serves the interests of all professionals concerned with these topics. By design, the journal is international and multidisciplinary in its approach, and members of the editorial board take an active role in the its mission, helping to make it the essential journal in paediatric cardiology. All aspects of paediatric cardiology are covered within the journal. The content includes original articles, brief reports, editorials, reviews, and papers devoted to continuing professional development.