缝合星状角膜裂伤的新技术

IF 1.9 3区 医学 Q2 OPHTHALMOLOGY Cornea Pub Date : 2025-04-01 Epub Date: 2024-10-29 DOI:10.1097/ICO.0000000000003730
Steven E Brooks, Alex Johnson, Emily A Kreuger
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引用次数: 0

摘要

目的:本研究旨在评估和优化在湿实验室环境下闭合星状角膜裂伤的新技术:21 只活体猪眼睛上的星状角膜裂伤是通过实验制作的标准化角膜裂伤,我们将其分配给三种手术修复技术中的一种。第一组(9 人)仅用简单的间断缝合法缝合裂口。第二组(n = 7)在简单间断缝合的基础上,使用大半径中央缝合线。在第 3 组(n = 5)中,除了简单间断缝合外,还使用了小半径中央荷包线。通过确定发生伤口渗漏时的眼压来评估伤口的稳定性:结果:第 3 组的平均伤口渗漏眼压为 56.1 毫米汞柱(范围为 32-90.3),而第 1 组和第 2 组的平均伤口渗漏眼压分别为 6.4 毫米汞柱(范围为 1.9-19)和 13.3 毫米汞柱(范围为 2.8-31)。这些差异具有高度统计学意义(P 讨论):使用小半径内荷包线缝合,再加上简单的间断缝合,可在实验性星状角膜裂伤中实现高效的水密性闭合,明显优于仅使用间断缝合或大半径荷包线的方法。在修复星状角膜裂伤的临床应用中,应考虑使用小半径荷包线缝合。
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Novel Technique to Close Stellate Corneal Lacerations.

Purpose: The study was performed to evaluate and optimize a novel technique to close stellate corneal lacerations in a wet laboratory environment.

Materials and methods: Twenty-one ex vivo porcine eyes with standardized, experimentally created stellate corneal lacerations were assigned to one of three surgical repair techniques. In Group 1 (n = 9), lacerations were closed with simple interrupted sutures only. In Group 2 (n = 7), a large-radius central purse string was used in addition to simple interrupted sutures. In Group 3 (n = 5), a small-radius central purse string was used in addition to simple interrupted sutures. Wound stability was assessed by determining the intraocular pressure (IOP) at which wound leak occurred.

Results: Group 3 eyes demonstrated a mean wound leak IOP of 56.1 mm Hg (range 32-90.3) compared with groups 1 and 2, which demonstrated mean wound leak IOPs of 6.4 mm Hg (range 1.9-19) and 13.3 mm Hg (range 2.8-31), respectively. These differences were highly statistically significant ( P  < 0.002 and P  < 0.015, respectively, compared with Group 3).

Discussion: The use of a small-radius internal purse-string suture, when combined with simple interrupted sutures, produced a highly effective watertight closure in experimentally created stellate corneal lacerations, significantly outperforming approaches using only interrupted sutures or a large-radius purse string. The use of a small-radius purse-string suture should be considered for clinical use in the repair of stellate corneal lacerations.

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来源期刊
Cornea
Cornea 医学-眼科学
CiteScore
5.20
自引率
10.70%
发文量
354
审稿时长
3-6 weeks
期刊介绍: For corneal specialists and for all general ophthalmologists with an interest in this exciting subspecialty, Cornea brings together the latest clinical and basic research on the cornea and the anterior segment of the eye. Each volume is peer-reviewed by Cornea''s board of world-renowned experts and fully indexed in archival format. Your subscription brings you the latest developments in your field and a growing library of valuable professional references. Sponsored by The Cornea Society which was founded as the Castroviejo Cornea Society in 1975.
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