体重正常的中枢性肥胖症及其对 2 型糖尿病的影响。

IF 5.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Current Diabetes Reports Pub Date : 2024-11-06 DOI:10.1007/s11892-024-01559-x
Jing Bai, Yifan Zhang, Li He, Yang Zhao
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引用次数: 0

摘要

综述目的:本综述旨在对目前研究正常体重肥胖(NWO)和正常体重中心性肥胖(NWCO)对成人 2 型糖尿病影响的文献进行最新评述:共纳入 14 项研究,包括 9 项横断面研究和 5 项队列研究,受试者人数为 334 438 人。证据质量参差不齐。汇总的 NWO 患病率为 16.1%(95% CI:12.7-19.4),NWCO 患病率为 21.1%(95% CI:12.2-30.1)。女性和非亚洲人的 NWO 和 NWCO 患病率较高。该综述还显示,2 型糖尿病与 NWO 和 NWCO 显著相关(汇总 OR:1.82 [1.62,2.04],p
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Normal Weight Central Obesity and its Impact on Type 2 Diabetes Mellitus.

Purpose of review: The aim of this review is to provide an updated commentary on the current literature examining the impact of normal weight obesity (NWO) and normal weight central obesity (NWCO) on type 2 diabetes mellitus in adults.

Recent findings: Total 14 studies were included, comprising 9 cross-sectional and 5 cohort studies with 334,438 subjects. The quality of evidence was mixed. The pooled prevalence of NWO was 16.1% (95% CI: 12.7-19.4) and NWCO was 21.1% (95% CI: 12.2-30.1). The prevalence of NWO and NWCO higher in females and non-Asians. This review also showed that type 2 diabetes was significantly associated with NWO and NWCO (pooled OR: 1.82 [1.62, 2.04], p < 0.01, I2 = 64%). Subgroup analyses revealed consistent relationships between type 2 diabetes and NWO/NWCO across sex, region and definition approach. There was a relative high prevalence of NWO and NWCO, particularly in females and non-Asian populations. There was a consistent association of NWO/NWCO with type 2 diabetes. Implications for future research to guide intervention optimization in clinical practice and public health promotion are provided.

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来源期刊
CiteScore
9.80
自引率
0.00%
发文量
52
审稿时长
6-12 weeks
期刊介绍: The goal of this journal is to publish cutting-edge reviews on subjects pertinent to all aspects of diabetes epidemiology, pathophysiology, and management. We aim to provide incisive, insightful, and balanced contributions from leading experts in each relevant domain that will be of immediate interest to a wide readership of clinicians, basic scientists, and translational investigators. We accomplish this aim by appointing major authorities to serve as Section Editors in key subject areas across the discipline. Section Editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year on their topics, in a crisp and readable format. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.
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