Jiachen Liu, Qingjiang Xu, Xin Wang, Ronghua Pan, Lizhong Zheng, Yonghong Zhang, Xiaoya Shang, Nan Wang
{"title":"Monascus Monacolin 类似物的结构阐释和完整 NMR 光谱分配。","authors":"Jiachen Liu, Qingjiang Xu, Xin Wang, Ronghua Pan, Lizhong Zheng, Yonghong Zhang, Xiaoya Shang, Nan Wang","doi":"10.1002/mrc.5489","DOIUrl":null,"url":null,"abstract":"<p><p>One new monacolin analog, monacolin V (1), together with two new monacolin-like natural products, 6-hydroxyl monacolin P (2) and 3-keto monacolin S (3), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of <sup>1</sup>H and <sup>13</sup>C NMR data for three compounds were obtained by the aid of HSQC, HMBC, <sup>1</sup>H-<sup>1</sup>H COSY, and NOESY data. This is the first time that the NMR data of compounds 2 and 3 have been fully assigned.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Structural Elucidation and Complete NMR Spectral Assignments of Monascus Monacolin Analogs.\",\"authors\":\"Jiachen Liu, Qingjiang Xu, Xin Wang, Ronghua Pan, Lizhong Zheng, Yonghong Zhang, Xiaoya Shang, Nan Wang\",\"doi\":\"10.1002/mrc.5489\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>One new monacolin analog, monacolin V (1), together with two new monacolin-like natural products, 6-hydroxyl monacolin P (2) and 3-keto monacolin S (3), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of <sup>1</sup>H and <sup>13</sup>C NMR data for three compounds were obtained by the aid of HSQC, HMBC, <sup>1</sup>H-<sup>1</sup>H COSY, and NOESY data. This is the first time that the NMR data of compounds 2 and 3 have been fully assigned.</p>\",\"PeriodicalId\":18142,\"journal\":{\"name\":\"Magnetic Resonance in Chemistry\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Magnetic Resonance in Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1002/mrc.5489\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magnetic Resonance in Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/mrc.5489","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Structural Elucidation and Complete NMR Spectral Assignments of Monascus Monacolin Analogs.
One new monacolin analog, monacolin V (1), together with two new monacolin-like natural products, 6-hydroxyl monacolin P (2) and 3-keto monacolin S (3), were isolated from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were identified by HRESIMS and NMR experiments, and the complete assignments of 1H and 13C NMR data for three compounds were obtained by the aid of HSQC, HMBC, 1H-1H COSY, and NOESY data. This is the first time that the NMR data of compounds 2 and 3 have been fully assigned.
期刊介绍：
MRC is devoted to the rapid publication of papers which are concerned with the development of magnetic resonance techniques, or in which the application of such techniques plays a pivotal part. Contributions from scientists working in all areas of NMR, ESR and NQR are invited, and papers describing applications in all branches of chemistry, structural biology and materials chemistry are published.
The journal is of particular interest not only to scientists working in academic research, but also those working in commercial organisations who need to keep up-to-date with the latest practical applications of magnetic resonance techniques.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
