L5 形态学对预防脊柱退行性病变浮动融合术后 L5-S1 退化的影响

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-11-06 DOI:10.1177/21925682241297934
Xiaolong Lin, Jie Zhu, Jincheng Song, Liming Wang, Jianfei Ge, Weiping Sha
{"title":"L5 形态学对预防脊柱退行性病变浮动融合术后 L5-S1 退化的影响","authors":"Xiaolong Lin, Jie Zhu, Jincheng Song, Liming Wang, Jianfei Ge, Weiping Sha","doi":"10.1177/21925682241297934","DOIUrl":null,"url":null,"abstract":"<p><strong>Study design: </strong>Retrospective Study.</p><p><strong>Objectives: </strong>The selection of floating fusion or lumbosacral fusion arises when treating patients with instability or stenosis of the lower lumbar spine concomitantly radiographic degeneration of L5-S1. This study aimed to investigate the preoperative anatomical or morphological factors affecting the survivorship of the L5-S1 after floating fusion.</p><p><strong>Methods: </strong>This study included 77 patients who had undergone floating fusion surgery through the TLIF approach. Preoperative radiographic parameters were evaluated using anteroposterior and lateral lumbar spine radiographs. The patients were divided into two groups according to the Modified Pfirrmann Grading and total endplate score. Multivariable regression analysis was performed to explore the relationships between the anatomical or morphological characteristics of L5 and the degeneration of L5-S1.</p><p><strong>Results: </strong>The disc degeneration group exhibited a smaller height ratio of the iliac crest (H<sub><i>i</i></sub>) and a less L5 deep position. Furthermore, the right/left height of L4 (H<sub><i>r</i></sub>/H<sub><i>l</i></sub>) and the right/left width of transverse process of L5 (C<sub><i>Rt</i></sub>/C<sub><i>Lt</i></sub>) were significantly higher in the disc and endplate degeneration groups. Multiple logistic regression analysis revealed that H<sub><i>i</i></sub> and C<sub><i>Rt</i></sub> were independently associated with L5-S1 disc degeneration, whereas H<sub><i>r</i></sub> was a significant risk factor for L5-S1 endplate degeneration.</p><p><strong>Conclusion: </strong>Anatomical and morphological characteristics of L5, such as smaller H<sub><i>i</i></sub>, higher C<sub><i>Rt</i></sub> and H<sub><i>r</i></sub>, were associated with an increased risk of L5-S1 degeneration in patients after floating fusion. These findings may indicate the fusion level when addressing lower lumbar degenerative diseases and the concurrent radiographic degeneration of L5-S1.</p>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559769/pdf/","citationCount":"0","resultStr":"{\"title\":\"The Effect of L5 Morphology on Prevention of L5-S1 Degeneration Following Floating Fusion for Degenerative Spine Disorders.\",\"authors\":\"Xiaolong Lin, Jie Zhu, Jincheng Song, Liming Wang, Jianfei Ge, Weiping Sha\",\"doi\":\"10.1177/21925682241297934\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Study design: </strong>Retrospective Study.</p><p><strong>Objectives: </strong>The selection of floating fusion or lumbosacral fusion arises when treating patients with instability or stenosis of the lower lumbar spine concomitantly radiographic degeneration of L5-S1. This study aimed to investigate the preoperative anatomical or morphological factors affecting the survivorship of the L5-S1 after floating fusion.</p><p><strong>Methods: </strong>This study included 77 patients who had undergone floating fusion surgery through the TLIF approach. Preoperative radiographic parameters were evaluated using anteroposterior and lateral lumbar spine radiographs. The patients were divided into two groups according to the Modified Pfirrmann Grading and total endplate score. Multivariable regression analysis was performed to explore the relationships between the anatomical or morphological characteristics of L5 and the degeneration of L5-S1.</p><p><strong>Results: </strong>The disc degeneration group exhibited a smaller height ratio of the iliac crest (H<sub><i>i</i></sub>) and a less L5 deep position. Furthermore, the right/left height of L4 (H<sub><i>r</i></sub>/H<sub><i>l</i></sub>) and the right/left width of transverse process of L5 (C<sub><i>Rt</i></sub>/C<sub><i>Lt</i></sub>) were significantly higher in the disc and endplate degeneration groups. Multiple logistic regression analysis revealed that H<sub><i>i</i></sub> and C<sub><i>Rt</i></sub> were independently associated with L5-S1 disc degeneration, whereas H<sub><i>r</i></sub> was a significant risk factor for L5-S1 endplate degeneration.</p><p><strong>Conclusion: </strong>Anatomical and morphological characteristics of L5, such as smaller H<sub><i>i</i></sub>, higher C<sub><i>Rt</i></sub> and H<sub><i>r</i></sub>, were associated with an increased risk of L5-S1 degeneration in patients after floating fusion. These findings may indicate the fusion level when addressing lower lumbar degenerative diseases and the concurrent radiographic degeneration of L5-S1.</p>\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-11-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559769/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/21925682241297934\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/21925682241297934","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0

摘要

研究设计回顾性研究:在治疗下腰椎不稳定或狭窄并伴有L5-S1放射性退变的患者时,需要选择浮动融合术或腰骶融合术。本研究旨在探讨影响浮动融合术后L5-S1存活率的术前解剖学或形态学因素:本研究纳入了 77 例通过 TLIF 方法接受浮动融合手术的患者。通过腰椎正、侧位片对术前影像学参数进行评估。根据改良 Pfirrmann 分级和终板总评分将患者分为两组。对 L5 的解剖或形态特征与 L5-S1 椎间盘退变之间的关系进行了多变量回归分析:结果:椎间盘退变组的髂嵴高度比(Hi)较小,L5深度位置较低。此外,椎间盘和终板退变组的L4左右高度(Hr/Hl)和L5横突右/左宽度(CRt/CLt)均显著增高。多元逻辑回归分析显示,Hi和CRt与L5-S1椎间盘退变独立相关,而Hr则是L5-S1终板退变的重要风险因素:结论:L5的解剖和形态特征,如较小的Hi、较高的CRt和Hr,与浮动融合术后患者L5-S1退变风险的增加有关。这些发现可能预示着在处理下腰椎退行性疾病时的融合水平,以及 L5-S1 的并发影像学退变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The Effect of L5 Morphology on Prevention of L5-S1 Degeneration Following Floating Fusion for Degenerative Spine Disorders.

Study design: Retrospective Study.

Objectives: The selection of floating fusion or lumbosacral fusion arises when treating patients with instability or stenosis of the lower lumbar spine concomitantly radiographic degeneration of L5-S1. This study aimed to investigate the preoperative anatomical or morphological factors affecting the survivorship of the L5-S1 after floating fusion.

Methods: This study included 77 patients who had undergone floating fusion surgery through the TLIF approach. Preoperative radiographic parameters were evaluated using anteroposterior and lateral lumbar spine radiographs. The patients were divided into two groups according to the Modified Pfirrmann Grading and total endplate score. Multivariable regression analysis was performed to explore the relationships between the anatomical or morphological characteristics of L5 and the degeneration of L5-S1.

Results: The disc degeneration group exhibited a smaller height ratio of the iliac crest (Hi) and a less L5 deep position. Furthermore, the right/left height of L4 (Hr/Hl) and the right/left width of transverse process of L5 (CRt/CLt) were significantly higher in the disc and endplate degeneration groups. Multiple logistic regression analysis revealed that Hi and CRt were independently associated with L5-S1 disc degeneration, whereas Hr was a significant risk factor for L5-S1 endplate degeneration.

Conclusion: Anatomical and morphological characteristics of L5, such as smaller Hi, higher CRt and Hr, were associated with an increased risk of L5-S1 degeneration in patients after floating fusion. These findings may indicate the fusion level when addressing lower lumbar degenerative diseases and the concurrent radiographic degeneration of L5-S1.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊最新文献
A Systematic Review of Sleep Disturbance in Idiopathic Intracranial Hypertension. Advancing Patient Education in Idiopathic Intracranial Hypertension: The Promise of Large Language Models. Anti-Myelin-Associated Glycoprotein Neuropathy: Recent Developments. Approach to Managing the Initial Presentation of Multiple Sclerosis: A Worldwide Practice Survey. Association Between LACE+ Index Risk Category and 90-Day Mortality After Stroke.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1