脂质纳米颗粒中的多重 RNA：慢性乙型肝炎的潜在治疗疫苗

IF 4.3 2区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR Inorganic Chemistry Pub Date : 2024-11-07 DOI:10.1038/s41392-024-02026-5

Hari Krishnareddy Rachamala, Srujan Marepally

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引用次数: 0

摘要

Z. Wenjing 和 Min Y. 等人最近在《信号转导与靶向治疗》（Signal Transduction and Targeted Therapy）杂志上发表的一项研究可能会改变慢性乙型肝炎感染领域的游戏规则。研究重点是利用脂质纳米颗粒递送多重 RNA，探索针对乙型肝炎病毒（HBV）的双重小干扰 RNA（siRNA）与白细胞介素-2（IL-2）mRNA 一起调节免疫反应的协同效应1。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Multiplexed RNAs in lipid nanoparticles: potential therapeutic vaccine for chronic hepatitis B

A recent study published in Signal Transduction and Targeted Therapy by Wenjing Z. and Min Y. et al. presents a potential game-changer in the field of chronic hepatitis B infection. The research focuses on the delivery of multiplexed RNAs using lipid nanoparticles, exploring the synergistic effects of dual small interfering RNAs (siRNAs) targeting the hepatitis B virus (HBV) alongside modulating immune responses with interleukin-2 (IL-2) mRNA.¹

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来源期刊

Inorganic Chemistry 化学-无机化学与核化学

CiteScore

7.60

自引率

13.00%

发文量

1960

审稿时长

1.9 months

期刊介绍： Inorganic Chemistry publishes fundamental studies in all phases of inorganic chemistry. Coverage includes experimental and theoretical reports on quantitative studies of structure and thermodynamics, kinetics, mechanisms of inorganic reactions, bioinorganic chemistry, and relevant aspects of organometallic chemistry, solid-state phenomena, and chemical bonding theory. Emphasis is placed on the synthesis, structure, thermodynamics, reactivity, spectroscopy, and bonding properties of significant new and known compounds.