{"title":"(Z)-N3-(2-氨基-1,2-二氰基乙烯基)甲酰胺腙与五元 N-杂环的官能化及其抗菌活性","authors":"A. Al-Azmi, E. John","doi":"10.1134/S1070428024090173","DOIUrl":null,"url":null,"abstract":"<p>Various five-membered heterocyclic compounds and highly functionalized open intermediates were simply synthesized by reacting (<i>Z</i>)–<i>N</i><sup>3</sup>-(2-amino-1,2-dicyanovinyl)formamidrazone with selected reagents containing electrophilic carbon. The synthesized compounds were tested for antimicrobial activity and were found to have moderate antimicrobial effects.</p>","PeriodicalId":766,"journal":{"name":"Russian Journal of Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Functionalization of (Z)-N3-(2-Amino-1,2-dicyanovinyl)formamidrazone to Five-Membered N-Heterocycles and Their Antimicrobial Activity\",\"authors\":\"A. Al-Azmi, E. John\",\"doi\":\"10.1134/S1070428024090173\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Various five-membered heterocyclic compounds and highly functionalized open intermediates were simply synthesized by reacting (<i>Z</i>)–<i>N</i><sup>3</sup>-(2-amino-1,2-dicyanovinyl)formamidrazone with selected reagents containing electrophilic carbon. The synthesized compounds were tested for antimicrobial activity and were found to have moderate antimicrobial effects.</p>\",\"PeriodicalId\":766,\"journal\":{\"name\":\"Russian Journal of Organic Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-11-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1070428024090173\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070428024090173","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Functionalization of (Z)-N3-(2-Amino-1,2-dicyanovinyl)formamidrazone to Five-Membered N-Heterocycles and Their Antimicrobial Activity
Various five-membered heterocyclic compounds and highly functionalized open intermediates were simply synthesized by reacting (Z)–N3-(2-amino-1,2-dicyanovinyl)formamidrazone with selected reagents containing electrophilic carbon. The synthesized compounds were tested for antimicrobial activity and were found to have moderate antimicrobial effects.
期刊介绍：
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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