B. V. Chal’tsev, A. S. Burlov, V. G. Vlasenko, Yu. V. Koshchienko, A. A. Zubenko, A. I. Klimenko, V. A. Lazarenko, S. A. Mashchenko, E. V. Korshunova, T. V. Lifintseva
{"title":"2-(N-对甲苯磺酰基氨基)苯甲醛苯甲酰腙铜(II)配合物：合成、结构、性质和生物活性","authors":"B. V. Chal’tsev, A. S. Burlov, V. G. Vlasenko, Yu. V. Koshchienko, A. A. Zubenko, A. I. Klimenko, V. A. Lazarenko, S. A. Mashchenko, E. V. Korshunova, T. V. Lifintseva","doi":"10.1134/S1070328424600438","DOIUrl":null,"url":null,"abstract":"<p>A number of new copper(II) complexes of 2-(<i>N</i>-tosylamino)benzaldehyde benzoylhydrazone (H<sub>2</sub>L) CuLL<sup><i>n</i></sup> (<i>n</i> = 1–6) with heterocyclic donor ligands (L<sup>1</sup> = 1-propyl-2-aminobenzimidazole, L<sup>2</sup> = 1‑hexyl-2-aminobenzimidazole, L<sup>3</sup> = 1-octyl-2-aminobenzimidazole, L<sup>4</sup> = 2,2'-bipyridine, L<sup>5</sup> = 1,10-phenanthroline, and L<sup>6</sup> = 2-aminopyridine) is synthesized. The structures and compositions of the synthesized compounds are determined by elemental analysis, <sup>1</sup>Н NMR spectroscopy, IR spectroscopy, and magnetochemistry. The molecular structures of complexes CuLL<sup>1,2,4−6</sup> are determined by XRD (CIF files CCDC nos. 2341480 (CuLL<sup>1</sup>), 2341468 (CuLL<sup>2</sup>), 2341478 (CuLL<sup>4</sup>), 2341477 (CuLL<sup>5</sup>), and 2341479 (CuLL<sup>6</sup>)). The biological activity of the complexes is studied. The adducts with L<sup>1</sup>, L<sup>2</sup>, and L<sup>6</sup> exhibit a significantly higher anti-protist activity than chloroquine used as the reference compound.</p>","PeriodicalId":759,"journal":{"name":"Russian Journal of Coordination Chemistry","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Copper(II) 2-(N-Tosylamino)benzaldehyde Benzoylhydrazone Complexes: Synthesis, Structures, Properties, and Biological Activity\",\"authors\":\"B. V. Chal’tsev, A. S. Burlov, V. G. Vlasenko, Yu. V. Koshchienko, A. A. Zubenko, A. I. Klimenko, V. A. Lazarenko, S. A. Mashchenko, E. V. Korshunova, T. V. Lifintseva\",\"doi\":\"10.1134/S1070328424600438\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A number of new copper(II) complexes of 2-(<i>N</i>-tosylamino)benzaldehyde benzoylhydrazone (H<sub>2</sub>L) CuLL<sup><i>n</i></sup> (<i>n</i> = 1–6) with heterocyclic donor ligands (L<sup>1</sup> = 1-propyl-2-aminobenzimidazole, L<sup>2</sup> = 1‑hexyl-2-aminobenzimidazole, L<sup>3</sup> = 1-octyl-2-aminobenzimidazole, L<sup>4</sup> = 2,2'-bipyridine, L<sup>5</sup> = 1,10-phenanthroline, and L<sup>6</sup> = 2-aminopyridine) is synthesized. The structures and compositions of the synthesized compounds are determined by elemental analysis, <sup>1</sup>Н NMR spectroscopy, IR spectroscopy, and magnetochemistry. The molecular structures of complexes CuLL<sup>1,2,4−6</sup> are determined by XRD (CIF files CCDC nos. 2341480 (CuLL<sup>1</sup>), 2341468 (CuLL<sup>2</sup>), 2341478 (CuLL<sup>4</sup>), 2341477 (CuLL<sup>5</sup>), and 2341479 (CuLL<sup>6</sup>)). The biological activity of the complexes is studied. The adducts with L<sup>1</sup>, L<sup>2</sup>, and L<sup>6</sup> exhibit a significantly higher anti-protist activity than chloroquine used as the reference compound.</p>\",\"PeriodicalId\":759,\"journal\":{\"name\":\"Russian Journal of Coordination Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2024-11-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Coordination Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1070328424600438\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Coordination Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070328424600438","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Copper(II) 2-(N-Tosylamino)benzaldehyde Benzoylhydrazone Complexes: Synthesis, Structures, Properties, and Biological Activity
A number of new copper(II) complexes of 2-(N-tosylamino)benzaldehyde benzoylhydrazone (H2L) CuLLn (n = 1–6) with heterocyclic donor ligands (L1 = 1-propyl-2-aminobenzimidazole, L2 = 1‑hexyl-2-aminobenzimidazole, L3 = 1-octyl-2-aminobenzimidazole, L4 = 2,2'-bipyridine, L5 = 1,10-phenanthroline, and L6 = 2-aminopyridine) is synthesized. The structures and compositions of the synthesized compounds are determined by elemental analysis, 1Н NMR spectroscopy, IR spectroscopy, and magnetochemistry. The molecular structures of complexes CuLL1,2,4−6 are determined by XRD (CIF files CCDC nos. 2341480 (CuLL1), 2341468 (CuLL2), 2341478 (CuLL4), 2341477 (CuLL5), and 2341479 (CuLL6)). The biological activity of the complexes is studied. The adducts with L1, L2, and L6 exhibit a significantly higher anti-protist activity than chloroquine used as the reference compound.
期刊介绍：
Russian Journal of Coordination Chemistry is a journal that publishes reviews, original papers, and short communications on all aspects of theoretical and experimental coordination chemistry. Modern coordination chemistry is an interdisciplinary science that makes a bridge between inorganic, organic, physical, analytical, and biological chemistry.
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