韩国老年人群骨质疏松症发病率及其相关因素:基于人群的队列研究结果

IF 3.1 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Archives of Osteoporosis Pub Date : 2024-11-08 DOI:10.1007/s11657-024-01466-4
Tanmoy Das, Md Abdullah Al Jubayer Biswas, Prosanta Mondal, Sabuj Sarker, Hyun J.“June” Lim
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引用次数: 0

摘要

摘要在韩国,老年人骨质疏松症的发病率尚不明确。我们的研究显示,每 1000 人年中有 18.4 人患骨质疏松症,女性和受教育程度较低的老年人患骨质疏松症的比例较高。研究结果表明,有必要制定有针对性的预防策略,以指导改善老年人骨质疏松症护理的卫生政策。研究背景虽然骨质疏松症严重影响韩国老年人口的发病率和死亡率,但这一人口群体中的骨质疏松症发病率及其相关因素仍不清楚。方法我们分析了韩国全国健康面板调查(一项具有全国代表性的、基于人口的面板调查,调查时间跨度为 2008 年至 2018 年)的数据,计算了韩国 50 岁及以上老年人的骨质疏松症发病率。结果在参与分析的 7304 名研究参与者中,我们发现了 792 例骨质疏松症事件,总累积发病率为每 1000 人-年 18.4 例。骨质疏松症的发病率随着年龄的增长而稳步上升,在教育程度较低的人群中发病率更高。我们还发现,与男性相比,女性研究参与者患骨质疏松症的风险在统计学上显著高出 7.2 倍(aHR = 7.2,95% CI = 5.8-8.8)。与此同时,患有高脂血症的人患骨质疏松症的风险在统计学上显著增加了 1.3 倍(aHR = 1.3,95% CI = 1.1-1.4)。这表明政府和医疗系统迫切需要考虑骨质疏松症的诊断和预防策略,以确保韩国老年人口的健康和福祉。
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Osteoporosis incidence and its associated factors in the older Korean population: findings from a population-based cohort study

Summary

In South Korea, osteoporosis incidence among the elderly was unclear. Our study revealed an incidence of 18.4 per 1000 person-years, with higher rates in females and those with lower education. The findings indicate a need for targeted prevention strategies to guide health policy for improved osteoporosis care for the elderly.

Background

Although osteoporosis significantly affects morbidity and mortality among the older population in South Korea, the incidence of osteoporosis and its associated factors within this demographic group remains unclear.

Method

We analyzed data from the Korean National Health Panel Survey, a nationally representative, population-based panel survey covering 2008 to 2018, to compute the incidence of osteoporosis among South Koreans aged 50 and older. Using the stepwise Cox Proportional Hazard model, we then identified and determined the associated factors of osteoporosis.

Result

Out of the 7304 study participants in our analysis, we identified 792 osteoporosis events, resulting in an overall cumulative incidence rate of 18.4 per 1000 person-years. The incidence of osteoporosis increased steadily with age and was higher among those with lower levels of education. We also found that female study participants were at a statistically significant 7.2-fold higher risk (aHR = 7.2, 95% CI = 5.8–8.8) of developing osteoporosis compared to males. At the same time, those with hyperlipidemia had a statistically significant 1.3-fold increased risk (aHR = 1.3, 95% CI = 1.1–1.4) of developing osteoporosis.

Conclusion

Our study highlights a significant proportion of the older South Korean population developed osteoporosis, especially among those who are older, females, and who have hyperlipidemia. This indicates the pressing need for the government’s and healthcare systems’ consideration of osteoporosis diagnosis and prevention strategies to ensure the health and well-being of the older South Korean population.

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来源期刊
Archives of Osteoporosis
Archives of Osteoporosis ENDOCRINOLOGY & METABOLISMORTHOPEDICS -ORTHOPEDICS
CiteScore
5.50
自引率
10.00%
发文量
133
期刊介绍: Archives of Osteoporosis is an international multidisciplinary journal which is a joint initiative of the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA. The journal will highlight the specificities of different regions around the world concerning epidemiology, reference values for bone density and bone metabolism, as well as clinical aspects of osteoporosis and other bone diseases.
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