利用 4-Aminocumarin 单锅多组分合成被取代的 1,6-萘啶衍生物

IF 3.7 2区 化学 Q2 CHEMISTRY, APPLIED Applied Organometallic Chemistry Pub Date : 2024-09-30 DOI:10.1002/aoc.7718
Elham Ezzatzadeh, Mahsa Hojjati, Azadeh Parhami, Zinatossadat Hossaini
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引用次数: 0

摘要

本研究利用多组分反应高效合成了 1,6-萘啶这一类新型融合杂环化合物。该反应涉及室温下水溶液中的苯甲醛或其衍生物、2 mol 丙二腈和 4-aminocumarin,以 SiO2/Fe3O4@MWCNTs 为可循环催化剂。本研究除了探讨 1,6-萘啶的抗氧化特性外,还对其进行了其他研究。1,6-萘啶的生产工艺显示出若干优势特点,包括反应快速、最终产品收率高、催化剂和产品可从反应混合物中直接分离。
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One-Pot Multicomponent Synthesis of Substituted 1,6-Naphthyridine Derivatives Employing 4-Aminocumarin

This study synthesized 1,6-naphthyridine as a novel class of fused heterocyclic compounds with high efficiency using a multicomponent reaction. The reaction involved benzaldehyde or its derivatives, 2 mol of malononitrile, and 4-aminocumarin in an aqueous solution at room temperature in the presence of SiO2/Fe3O4@MWCNTs as a recyclable catalyst. This study examines the antioxidant properties of 1,6-naphthyridine in addition to the other research undertaken in this work. The production process of 1,6-naphthyridine demonstrated several advantageous features, including rapid reactions, high yields of the final product, and straightforward separation of the catalyst and product from the reaction mixture.

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来源期刊
Applied Organometallic Chemistry
Applied Organometallic Chemistry 化学-无机化学与核化学
CiteScore
7.80
自引率
10.30%
发文量
408
审稿时长
2.2 months
期刊介绍: All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.
期刊最新文献
Issue Information Issue Information One-Pot Multicomponent Synthesis of Substituted 1,6-Naphthyridine Derivatives Employing 4-Aminocumarin The Role of L-Ligands in Silica-Supported Ti Oxo/Imido Heterometathesis Catalysts Cover Image
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