Advancing Paper-Based Sensors with MXenes and MOFs: Exploring the Cutting-Edge Innovations

MXenes and metal-organic frameworks (MOFs) are emerging as promising materials for integration into paper-based sensors (PSs), offering unique properties that can enhance sensor performance in various applications. MXenes, with their high conductivity and large surface area, and MOFs, known for their tunable porosity and chemical functionalities, bring distinct advantages to PSs. By leveraging the exceptional properties of MXenes and MOFs, researchers can develop PSs with improved sensitivity, selectivity, and stability, paving the way for advanced sensing platforms with diverse capabilities in environmental monitoring, healthcare diagnostics, and beyond. However, challenges are still existed in incorporating MXenes and MOFs into PSs, including sensitivity, stability, interference, and scalability. Addressing these challenges is crucial for optimizing sensor performance and reliability. Herein, recent developments pertaining to the applications of MXenes and MOFs in PSs are deliberated, focusing on challenges and future perspectives. By examining the unique properties of these materials, exploring innovative sensor designs, and discussing potential solutions to current challenges, this review seeks to pave the way for the development of next-generation PSs with enhanced sensitivity, selectivity, and reliability.