[转移性垂体病变]。

A M Lapshina, E A Bazarova, E G Przhialkovskaya, P M Khandaeva, V N Azizyan, A Yu Grigoriev, O V Ivashchenko, N V Tarbaeva, Zh E Belaya
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引用次数: 0

摘要

垂体转移性病变是一种罕见病,确诊率为 1.8%-4%。对这类患者的监测和治疗是一项复杂的任务,需要多学科专家团队的更多关注。作者介绍了三名患有转移性垂体病变的患者,他们在国家内分泌研究所的国家研究中心接受了神经外科治疗,随后进行了病理形态学确诊。原发肿瘤为乳腺癌、肺类癌和透明细胞肾癌。两名患者有垂体以外的远处转移。所有病例的临床表现均为泛垂体功能障碍、脉络膜综合征和肿块效应。手术治疗后的随访期为 0.25-2.5 年。有两名患者的基础疾病有所进展。其中一名患者接受了立体定向放射外科治疗和立体定向照射。一名患者病情稳定。
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[Metastatic pituitary lesion].

Metastatic lesion of pituitary is a rare condition and is diagnosed in 1.8-4% of cases. Monitoring and treatment of such patients is a complex task and requires increased attention from a multidisciplinary team of specialists. The authors represent three patients with metastatic pituitary lesion who underwent neurosurgical treatment at the National Research Center of the National Research Institute of Endocrinology with subsequent pathomorphological confirmation of the diagnosis. The primary tumors were breast cancer, lung carcinoid, and clear cell kidney cancer. Two patients had distant metastases other than the pituitary gland. The clinical manifestation consisted in the appearance of symptoms of panhypopituitarism, chiasmal syndrome and mass effect in all cases. The follow-up period after surgical treatment was 0.25-2.5 years. Progression of the underlying disease was noted in two patients. One of them carried out stereotactic radiosurgical treatment and stereotactic oriented irradiation. One patient has a stable condition.

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