新兴的分子医学时代

IF 15.8 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY ACS Nano Pub Date : 2024-10-30 DOI:10.1021/acsnano.4c0796910.1021/acsnano.4c07969
Heming Tang, Ying Zhang, Yanyuan Wu, Ting Fu, Cheng Cui, Zongping Wang, Sitao Xie*, Qin Wu* and Weihong Tan*, 
{"title":"新兴的分子医学时代","authors":"Heming Tang,&nbsp;Ying Zhang,&nbsp;Yanyuan Wu,&nbsp;Ting Fu,&nbsp;Cheng Cui,&nbsp;Zongping Wang,&nbsp;Sitao Xie*,&nbsp;Qin Wu* and Weihong Tan*,&nbsp;","doi":"10.1021/acsnano.4c0796910.1021/acsnano.4c07969","DOIUrl":null,"url":null,"abstract":"<p >The era of molecular medicine arose as we began to diagnose and treat diseases based on understanding how genes, proteins, and cells work, providing optimal therapeutic care through molecular profiling. Central to molecular medicine is molecular recognition, which is underpinned by techniques involving omics analysis, gene editing, and targeted agents. Recent advancements in these tools not only expand our understanding of biological processes but also aid in the development of diagnostic and treatment modalities at the molecular level, thus bridging the gap between medical research and clinical applications. This perspective traces the development of molecular tools, highlighting, along the way, their pivotal role in advancing molecular medicine for the global health of people.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"18 45","pages":"30911–30918 30911–30918"},"PeriodicalIF":15.8000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Emerging Era of Molecular Medicine\",\"authors\":\"Heming Tang,&nbsp;Ying Zhang,&nbsp;Yanyuan Wu,&nbsp;Ting Fu,&nbsp;Cheng Cui,&nbsp;Zongping Wang,&nbsp;Sitao Xie*,&nbsp;Qin Wu* and Weihong Tan*,&nbsp;\",\"doi\":\"10.1021/acsnano.4c0796910.1021/acsnano.4c07969\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >The era of molecular medicine arose as we began to diagnose and treat diseases based on understanding how genes, proteins, and cells work, providing optimal therapeutic care through molecular profiling. Central to molecular medicine is molecular recognition, which is underpinned by techniques involving omics analysis, gene editing, and targeted agents. Recent advancements in these tools not only expand our understanding of biological processes but also aid in the development of diagnostic and treatment modalities at the molecular level, thus bridging the gap between medical research and clinical applications. This perspective traces the development of molecular tools, highlighting, along the way, their pivotal role in advancing molecular medicine for the global health of people.</p>\",\"PeriodicalId\":21,\"journal\":{\"name\":\"ACS Nano\",\"volume\":\"18 45\",\"pages\":\"30911–30918 30911–30918\"},\"PeriodicalIF\":15.8000,\"publicationDate\":\"2024-10-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Nano\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acsnano.4c07969\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Nano","FirstCategoryId":"88","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsnano.4c07969","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

摘要

随着我们开始根据对基因、蛋白质和细胞工作原理的了解来诊断和治疗疾病,并通过分子剖析提供最佳治疗护理,分子医学时代应运而生。分子医学的核心是分子识别,而分子识别的基础是涉及全息分析、基因编辑和靶向药物的技术。这些工具的最新进展不仅拓展了我们对生物过程的理解,还有助于开发分子水平的诊断和治疗模式,从而缩小医学研究与临床应用之间的差距。本视角追溯了分子工具的发展历程,重点介绍了这些工具在推动分子医学发展、促进全球人类健康方面发挥的关键作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The Emerging Era of Molecular Medicine

The era of molecular medicine arose as we began to diagnose and treat diseases based on understanding how genes, proteins, and cells work, providing optimal therapeutic care through molecular profiling. Central to molecular medicine is molecular recognition, which is underpinned by techniques involving omics analysis, gene editing, and targeted agents. Recent advancements in these tools not only expand our understanding of biological processes but also aid in the development of diagnostic and treatment modalities at the molecular level, thus bridging the gap between medical research and clinical applications. This perspective traces the development of molecular tools, highlighting, along the way, their pivotal role in advancing molecular medicine for the global health of people.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
ACS Nano
ACS Nano 工程技术-材料科学:综合
CiteScore
26.00
自引率
4.10%
发文量
1627
审稿时长
1.7 months
期刊介绍: ACS Nano, published monthly, serves as an international forum for comprehensive articles on nanoscience and nanotechnology research at the intersections of chemistry, biology, materials science, physics, and engineering. The journal fosters communication among scientists in these communities, facilitating collaboration, new research opportunities, and advancements through discoveries. ACS Nano covers synthesis, assembly, characterization, theory, and simulation of nanostructures, nanobiotechnology, nanofabrication, methods and tools for nanoscience and nanotechnology, and self- and directed-assembly. Alongside original research articles, it offers thorough reviews, perspectives on cutting-edge research, and discussions envisioning the future of nanoscience and nanotechnology.
期刊最新文献
Targeting Metastasis in Head and Neck Squamous Cell Carcinoma Using Follistatin mRNA Lipid Nanoparticles Photocatalytic Achmatowicz Rearrangement on Triphenylbenzene–Dimethoxyterephthaldehyde–Covalent Organic Framework-Mo for Converting Biomass-Derived Furfuryl Alcohol to Hydropyranone Distinct Inflammatory Programs Underlie the Intramuscular Lipid Nanoparticle Response Spontaneous Lifting and Self-Cleaning of Gas Hydrate Crystals Design Considerations and Fabrication Protocols of High-Performance Intrinsically Stretchable Transistors and Integrated Circuits
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1