肩关节骨关节炎有助于确诊肢端肥大症。

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL BMJ Case Reports Pub Date : 2024-11-14 DOI:10.1136/bcr-2023-258545
Romain Garofoli, Domitille Renard, Laura Bessiene, Marie-Martine Lefèvre-Colau
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摘要

一名 50 岁出头的男子因机械性慢性疼痛和右肩活动范围受限前来就诊。肩部影像学检查显示肩部骨质增生,但无关节间隙变窄或肱骨头向头颅移位。他没有外伤史、关节脱位病史,也没有化脓性或炎症性关节炎、代谢性、嗜血性或内分泌相关关节病的临床或标准生物学证据。第二次就诊时发现手脚肿大和浸润。因此,我们怀疑是肢端肥大症,内分泌诊断证实了这一点。此外,脑垂体核磁共振成像显示存在鞘膜肿瘤。患者的肩部疼痛与未确诊的肢端肥大症关节病导致的骨关节炎有关,我们通过经蝶窦切除嗜体细胞腺瘤和服用体生长抑素类似物进行了治疗。总之,肢端肥大症应在盂肱骨骨关节炎患者中予以考虑,因为早期诊断对限制并发症和保持生活质量至关重要。
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Shoulder osteoarthritis facilitating the diagnosis of acromegaly.

A man in his early 50s presented with mechanical chronic pain and limitation of the active range of motion of the right shoulder. Imaging of the shoulder showed osteophytosis without joint space narrowing or cranial migration of the humeral head. He reported no history of trauma, dislocation arthropathy, clinical or standard biological evidence for septic or inflammatory arthritis, metabolic, haemophilic or endocrine-associated arthropathies. The second medical consultation revealed enlargement and infiltration of hands and feet. Consequently, we suspected acromegaly, which was confirmed by endocrinological diagnosis. Further, an MRI of the pituitary gland showed a sellar tumour. The patient's shoulder pain was related to undiagnosed acromegalic arthropathy leading to osteoarthritis and was treated by trans-sphenoidal exeresis of the somatotroph adenoma and a somatostatin analogue. In conclusion, acromegaly should be considered in patients with centred glenohumeral osteoarthritis, as an early diagnosis is essential to limit complications and preserve the quality of life.

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来源期刊
BMJ Case Reports
BMJ Case Reports Medicine-Medicine (all)
CiteScore
1.40
自引率
0.00%
发文量
1588
期刊介绍: BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.
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