分析肝肾移植患者性别对生活质量的影响

IF 2.4 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Healthcare Pub Date : 2024-10-23 DOI:10.3390/healthcare12212116
Naiara Campillo Amo, Enrique Pérez Martínez, Ana van-der Hofstadt Gomis, Ana Carolina Londoño Ramírez, Carlos J van-der Hofstadt Román
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引用次数: 0

摘要

背景:肾移植和肝移植会影响接受这些手术的患者的生活质量。因此,本研究旨在分析肝脏和肾脏移植中与患者性别有关的可能差异,并确定其对生活质量的影响:对 147 名肝脏(70 人)和肾脏(77 人)功能衰竭的等待移植患者进行了观察研究。研究分析了性别对移植前和移植后 6 个月患者生活质量的临床、社会人口和心理方面可能产生的影响。研究采用了健康相关生活质量(SF-36)、社会和家庭支持感(EASP)、应对策略(CEA)、抑郁和焦虑量表(HAD)以及艾森克人格量表(EPI)等问卷。使用包括卡方检验(Chi-square test)、t检验(t-test)和单变量线性方差分析(univariate linear analysis of variance)在内的统计工具,根据性别进行了单变量分析:结果:在等待肝移植的患者中,我们发现在年龄(p = 0.040)、终末期肝病的演变时间(p = 0.013)、病因(p = 0.07)、相关并发症以及吸烟和其他精神药物的摄入量(p = 0.022)方面存在性别差异,而等待肾移植的患者在病因(p = 0.012)和饮酒(p = 0.005)方面存在性别差异。结果显示,两组患者在社会人口学和心理方面存在明显的性别差异,但在两项评估中的总体生活质量方面均未观察到明显的性别差异:讨论:研究结果表明,肝脏或肾脏移植后生活质量的改善不受患者性别的影响。
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An Analysis of the Influence of a Patient's Sex on Quality of Life in Liver and Kidney Transplantation.

Background: Renal and liver transplantation influences the quality of life of the patients who undergo these procedures. Therefore, the aim of the present study was to analyze possible differences in liver and kidney transplantation in relation to the patient's sex and to determine their impact on quality of life.

Methodology: An observational study was carried out with 147 patients with liver (n = 70) and kidney (n = 77) failure on the transplantation waiting list. The possible influence of sex on clinical, sociodemographic, and psychological aspects of the patients' quality of life before and 6 months after transplantation was analyzed. Questionnaires on health-related quality of life (SF-36), the perception of social and family support (EASP), and coping strategies (CEA), the depression and anxiety scale (HAD), and the Eysenck personality inventory (EPI) were used. A univariate analysis was performed according to sex using statistical tools including the Chi-square test, the t-test, and a univariate linear analysis of variance.

Results: In patients on the waiting list for liver transplantation, we found sex differences in terms of age (p = 0.040), time of evolution of end-stage liver disease (p = 0.013), etiology (p = 0.07), and associated complications, as well as in the consumption of tobacco and other psychotropic substances (p = 0.022), while patients on the waiting list for renal transplantation showed sex-related differences in terms of etiology (p = 0.012) and alcohol consumption (p = 0.005). The results showed significant sex-related differences in sociodemographic and psychological aspects, but no significant sex-related differences were observed in global quality of life in either of the two assessments in both groups.

Discussion: The findings suggest that improvement in quality of life after liver or kidney transplantation is not influenced by the patient's sex.

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来源期刊
Healthcare
Healthcare Medicine-Health Policy
CiteScore
3.50
自引率
7.10%
发文量
0
审稿时长
47 days
期刊介绍: Healthcare (ISSN 2227-9032) is an international, peer-reviewed, open access journal (free for readers), which publishes original theoretical and empirical work in the interdisciplinary area of all aspects of medicine and health care research. Healthcare publishes Original Research Articles, Reviews, Case Reports, Research Notes and Short Communications. We encourage researchers to publish their experimental and theoretical results in as much detail as possible. For theoretical papers, full details of proofs must be provided so that the results can be checked; for experimental papers, full experimental details must be provided so that the results can be reproduced. Additionally, electronic files or software regarding the full details of the calculations, experimental procedure, etc., can be deposited along with the publication as “Supplementary Material”.
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