{"title":"通过双单光子发射计算机断层扫描成功治疗一名老年嗜酸性粒细胞增多症伴多血管炎引起的急性嗜酸性心肌炎。","authors":"Tomohito Inage, Toshio Katagiri, Masataka Kajiwara, Takashi Fujimura, Tadashi Yamamoto, Minh T Nguyen, Yukari Takase, Yoshitaka Hirooka","doi":"10.1536/ihj.24-384","DOIUrl":null,"url":null,"abstract":"<p><p>An 83-year-old man with a 5-month history of asthma presented to the emergency department with chest oppression and dyspnea. Electrocardiography showed ST-segment depression. Transthoracic echocardiography showed no asynergy with an ejection fraction of 62%. Coronary angiography revealed no stenosis. On day 3, he developed worsening dyspnea, cough, and rapidly progressive acute decompensated heart failure with abdominal purpura and lower extremity petechiae.Myocardial and skin biopsies revealed eosinophilic infiltration. He was diagnosed with acute eosinophilic myocarditis and heart failure due to eosinophilic granulomatosis with polyangiitis. Methylprednisolone pulse therapy dramatically improved his symptoms and congestion. Dual single-photon emission computed tomography after 1 year demonstrated lesion improvement.</p>","PeriodicalId":13711,"journal":{"name":"International heart journal","volume":" ","pages":"1177-1181"},"PeriodicalIF":1.2000,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Successful Treatment of Acute Eosinophilic Myocarditis due to Eosinophilic Granulomatosis with Polyangiitis in an Older Man, Followed by Dual Single Photon Emission Computed Tomography.\",\"authors\":\"Tomohito Inage, Toshio Katagiri, Masataka Kajiwara, Takashi Fujimura, Tadashi Yamamoto, Minh T Nguyen, Yukari Takase, Yoshitaka Hirooka\",\"doi\":\"10.1536/ihj.24-384\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>An 83-year-old man with a 5-month history of asthma presented to the emergency department with chest oppression and dyspnea. Electrocardiography showed ST-segment depression. Transthoracic echocardiography showed no asynergy with an ejection fraction of 62%. Coronary angiography revealed no stenosis. On day 3, he developed worsening dyspnea, cough, and rapidly progressive acute decompensated heart failure with abdominal purpura and lower extremity petechiae.Myocardial and skin biopsies revealed eosinophilic infiltration. He was diagnosed with acute eosinophilic myocarditis and heart failure due to eosinophilic granulomatosis with polyangiitis. Methylprednisolone pulse therapy dramatically improved his symptoms and congestion. Dual single-photon emission computed tomography after 1 year demonstrated lesion improvement.</p>\",\"PeriodicalId\":13711,\"journal\":{\"name\":\"International heart journal\",\"volume\":\" \",\"pages\":\"1177-1181\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International heart journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1536/ihj.24-384\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International heart journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1536/ihj.24-384","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
一名 83 岁的男子因胸部压迫感和呼吸困难到急诊科就诊，他有 5 个月的哮喘病史。心电图显示 ST 段压低。经胸超声心动图显示没有异能，射血分数为 62%。冠状动脉造影显示没有狭窄。第 3 天，他出现呼吸困难、咳嗽和快速进展的急性失代偿性心力衰竭，并伴有腹部紫癜和下肢瘀斑。他被诊断为嗜酸粒细胞性肉芽肿伴多血管炎引起的急性嗜酸性心肌炎和心力衰竭。甲基强的松龙脉冲疗法极大地改善了他的症状和充血。一年后，双单光子发射计算机断层扫描显示病变有所改善。
Successful Treatment of Acute Eosinophilic Myocarditis due to Eosinophilic Granulomatosis with Polyangiitis in an Older Man, Followed by Dual Single Photon Emission Computed Tomography.
An 83-year-old man with a 5-month history of asthma presented to the emergency department with chest oppression and dyspnea. Electrocardiography showed ST-segment depression. Transthoracic echocardiography showed no asynergy with an ejection fraction of 62%. Coronary angiography revealed no stenosis. On day 3, he developed worsening dyspnea, cough, and rapidly progressive acute decompensated heart failure with abdominal purpura and lower extremity petechiae.Myocardial and skin biopsies revealed eosinophilic infiltration. He was diagnosed with acute eosinophilic myocarditis and heart failure due to eosinophilic granulomatosis with polyangiitis. Methylprednisolone pulse therapy dramatically improved his symptoms and congestion. Dual single-photon emission computed tomography after 1 year demonstrated lesion improvement.
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