结肠癌患者急诊与择期手术结果的回顾性分析:单中心研究

IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Journal of Clinical Medicine Pub Date : 2024-10-30 DOI:10.3390/jcm13216533
Roxana Loriana Negruț, Adrian Coțe, Adrian Marius Maghiar
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引用次数: 0

摘要

简介:与择期手术相比,结肠癌的急诊手术干预往往因疾病的晚期状态和干预的紧迫性而导致较差的治疗效果。这项回顾性研究旨在评估结肠癌急诊治疗的管理情况,并评估患者预后的差异。研究在一家外科急诊中心进行,分析了 182 个病例,重点关注人口统计学、肿瘤特征、手术方法和患者预后。材料和方法:该研究是一项回顾性观察研究,涉及在一家外科急救中心接受结肠癌手术的 182 例患者。研究人员从医院病历中收集数据,包括人口统计学细节、肿瘤特征、手术干预细节和结果,以及炎症特征。统计分析包括描述性统计和 t 检验,标准显著性为 p <0.05。结果研究表明,急诊病例的院内存活率(75.42%)明显低于择期手术。急诊病例的中性粒细胞-淋巴细胞比值、血小板-淋巴细胞比值等炎症指标较高,表明全身应激反应加剧。急诊手术的造口和术后并发症发生率也较高。结论:结肠癌急诊手术与肿瘤更晚期、生理应激增加和临床效果较差有关。早期检测策略和积极的针对性筛查可减少紧急干预的需要。未来的研究应侧重于早期诊断方案和加强公共卫生策略,以尽量减少急诊,从而为结肠癌患者带来更好的治疗效果。
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A Retrospective Analysis of Emergency Versus Elective Surgical Outcomes in Colon Cancer Patients: A Single-Center Study.

Introduction: Emergency surgical interventions for colon cancer are often associated with poorer outcomes compared to elective surgeries due to the advanced state of the disease and the urgency of intervention. This retrospective study aimed to evaluate the management of emergency management of colon cancer and to evaluate differences in patient outcomes. Conducted at a single surgical emergency center, the study analyzed 182 cases, focusing on demographics, tumor characteristics, surgical methods and patient outcomes. Material and Methods: A retrospective observational study was conducted, involving 182 cases who underwent surgery for colon cancer in a single surgical emergency center. Data was collected from hospital records, encompassing demographic details, tumor characteristics, surgical intervention detail and outcomes, alongside with inflammatory profiles. Statistical analyses included descriptive statistics and t-tests with standard significance at p < 0.05. Results: The study showed that emergency cases had significantly poorer in-hospital survival rates (75.42%) compared to elective surgeries. Inflammatory markers such as Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio were higher in emergency cases, suggesting heightened systemic stress. Emergency surgery was also associated with a higher incidence of ostomy and postoperative complications. Conclusions: Emergency surgery for colon cancer is linked to more advanced tumors, increased physiological stress and lesser clinical outcomes. Early detection strategies and active targeted screening could reduce the need for emergency interventions. Future research should focus on early diagnosis protocols and enhancing public health strategies to minimize emergency presentations, thereby leading to better outcomes for colon cancer patients.

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来源期刊
Journal of Clinical Medicine
Journal of Clinical Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
5.70
自引率
7.70%
发文量
6468
审稿时长
16.32 days
期刊介绍: Journal of Clinical Medicine (ISSN 2077-0383), is an international scientific open access journal, providing a platform for advances in health care/clinical practices, the study of direct observation of patients and general medical research. This multi-disciplinary journal is aimed at a wide audience of medical researchers and healthcare professionals. Unique features of this journal: manuscripts regarding original research and ideas will be particularly welcomed.JCM also accepts reviews, communications, and short notes. There is no limit to publication length: our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible.
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