前结构时代接受心脏手术的痴呆症患者的国家治疗效果。

IF 1.5 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiothoracic Surgery Pub Date : 2024-11-13 DOI:10.1186/s13019-024-03120-z
Andrew Tang, Tal Eitan, Krish C Dewan, Guangjin Zhou, Brad F Rosinski, Siran M Koroukian, Lars G Svensson, A Marc Gillinov, Edward G Soltesz
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引用次数: 0

摘要

目的:随着人口老龄化和痴呆症发病率的上升,有关接受心血管手术的痴呆症患者的数据非常少。我们研究了全国范围内心血管手术痴呆患者的趋势和结果,以确定其对发病率、死亡率和出院处置的影响:从 2002 年到 2014 年,在全国住院患者抽样调查的 4,201,697 名心脏手术患者中,有 11,414 人(0.27%)在术前诊断出患有痴呆症。采用倾向分数匹配法来平衡痴呆组和非痴呆组。主要结果包括术后发病率、死亡率和出院到专业护理机构(SNF)的情况:痴呆症患者多为男性(67%)和65-84岁(84%)。与非痴呆症患者相比,痴呆症患者的术后死亡率较低(3.4% 对 4.6%,P 结论:尽管人口老龄化日益加剧,但痴呆症患者的发病率却在不断上升:尽管人口老龄化导致痴呆症发病率上升,但与非痴呆症患者相比,痴呆症患者接受心血管手术的院内死亡率较低,住院费用也相近。痴呆症患者更有可能出现并发症,需要出院到专业护理机构接受治疗。谨慎选择患者和有针对性的物理治疗可能有助于减轻一些与痴呆症相关的并发症。
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National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era.

Objective: With an aging population and higher prevalence of dementia, there is a paucity of data regarding dementia patients undergoing cardiovascular surgery. We examined the nationwide trends and outcomes of cardiovascular surgery patients with dementia to determine its effect on morbidity, mortality, and discharge disposition.

Methods: From 2002 to 2014, 11,414 (0.27%) of the 4,201,697 cardiac surgery patients from the Nationwide Inpatient Sample had a preoperative diagnosis of dementia. Propensity-score matching was used to balance dementia and non-dementia groups. Primary outcomes included postoperative morbidity, mortality, and discharge to skilled nursing facility (SNF).

Results: Dementia patients were more often male (67%) and 65-84 years old (84%). Postoperative mortality among patients with dementia was lower compared to patients without dementia (3.4% vs. 4.6%, p < 0.05). In dementia patients, there were more complications (65% vs. 60%, p < 0.01), more blood transfusions [OR 1.3, 95%CI (1.1, 1.5), p < 0.01] and delirium [OR 3.6, 95%CI (2.9, 4.5), p < 0.0001). Dementia patients (n = 5,623, 49.8%) were twice as likely to be discharged to SNF [OR 2.1, 95%CI (1.9, 2.4), p < 0.0001]. Dementia patients discharged to SNF more often had delirium (18.2% vs. 12%, p < 0.01), renal complications (17% vs. 8%, p < 0.01), and prolonged mechanical ventilation (15% vs. 8%, p < 0.01).

Conclusions: Despite an aging population with increasing prevalence of dementia, patients with dementia can undergo cardiovascular surgery with a lower in-hospital mortality and similar hospitalization costs compared to their non-dementia counterparts. Dementia patients are more likely to experience complications and require discharge to skilled nursing facility. Careful patient selection and targeted physical therapy may help mitigate some dementia associated complications.

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来源期刊
Journal of Cardiothoracic Surgery
Journal of Cardiothoracic Surgery 医学-心血管系统
CiteScore
2.50
自引率
6.20%
发文量
286
审稿时长
4-8 weeks
期刊介绍: Journal of Cardiothoracic Surgery is an open access journal that encompasses all aspects of research in the field of Cardiology, and Cardiothoracic and Vascular Surgery. The journal publishes original scientific research documenting clinical and experimental advances in cardiac, vascular and thoracic surgery, and related fields. Topics of interest include surgical techniques, survival rates, surgical complications and their outcomes; along with basic sciences, pediatric conditions, transplantations and clinical trials. Journal of Cardiothoracic Surgery is of interest to cardiothoracic and vascular surgeons, cardiothoracic anaesthesiologists, cardiologists, chest physicians, and allied health professionals.
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