通往高尔基体的阶梯VPS13B 有两条路可走

IF 7.4 1区 生物学 Q1 CELL BIOLOGY Journal of Cell Biology Pub Date : 2024-12-02 Epub Date: 2024-11-12 DOI:10.1083/jcb.202411005
Roger Pons Lanau, Felix Campelo
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引用次数: 0

摘要

VPS13 蛋白介导跨膜脂质转移。其中,VPS13B 与高尔基体膜有关,VPS13B 突变会导致科恩综合征。在本期中,Ugur 等人 (https://doi.org/10.1083/jcb.202311189) 和 Du 等人 (https://doi.org/10.1083/jcb.202402083) 揭示了新的 VPS13B 相互作用因子及其在高尔基体组织和贩运中的功能。
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Stairway to the Golgi: Two paths VPS13B can go by.

VPS13 proteins mediate lipid transfer across membranes. Among them, VPS13B is associated with Golgi membranes, and VPS13B mutations cause Cohen syndrome. In this issue, Ugur et al. (https://doi.org/10.1083/jcb.202311189) and Du et al. (https://doi.org/10.1083/jcb.202402083) reveal new VPS13B interactors and their functions in Golgi organization and trafficking.

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来源期刊
Journal of Cell Biology
Journal of Cell Biology 生物-细胞生物学
CiteScore
12.60
自引率
2.60%
发文量
213
审稿时长
1 months
期刊介绍: The Journal of Cell Biology (JCB) is a comprehensive journal dedicated to publishing original discoveries across all realms of cell biology. We invite papers presenting novel cellular or molecular advancements in various domains of basic cell biology, along with applied cell biology research in diverse systems such as immunology, neurobiology, metabolism, virology, developmental biology, and plant biology. We enthusiastically welcome submissions showcasing significant findings of interest to cell biologists, irrespective of the experimental approach.
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