海龟体内的抗菌药物代谢动力学研究:综述。

IF 1.5 4区 农林科学 Q3 PHARMACOLOGY & PHARMACY Journal of veterinary pharmacology and therapeutics Pub Date : 2024-11-12 DOI:10.1111/jvp.13492
Eric F Egelund, Alana Jula, Kathleen Rish, Anthony M Casapao
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引用次数: 0

摘要

海龟的生存面临着各种威胁,主要是人类活动造成的,如误捕、船只撞击、污染和气候变化。其中许多活动都会导致海龟生病或受伤,增加感染的风险。要适当有效地治疗感染,就必须了解抗菌剂的特性及其在不伤害海龟的情况下消灭微生物的能力。因此,可靠的药代动力学研究对于合理用药非常重要。在此,我们回顾了迄今为止有关海龟体内抗菌药物药代动力学特性的详细研究。
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Antimicrobial Pharmacokinetic Studies in Sea Turtles: A Review.

Sea turtles face various threats to survival, primarily due to human activities, such as bycatch, vessel strikes, pollution, and climate change. Many of these activities can lead to illness or injuries, increasing the risk of infection. Treating infections appropriately and effectively requires knowledge of antimicrobial properties and their ability to eradicate microbes without harm to the sea turtle. Robust pharmacokinetic studies, therefore, are important for appropriate dosing. Herein, we review the studies detailing the pharmacokinetic properties of antimicrobials in sea turtles conducted to date.

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来源期刊
CiteScore
3.10
自引率
15.40%
发文量
69
审稿时长
8-16 weeks
期刊介绍: The Journal of Veterinary Pharmacology and Therapeutics (JVPT) is an international journal devoted to the publication of scientific papers in the basic and clinical aspects of veterinary pharmacology and toxicology, whether the study is in vitro, in vivo, ex vivo or in silico. The Journal is a forum for recent scientific information and developments in the discipline of veterinary pharmacology, including toxicology and therapeutics. Studies that are entirely in vitro will not be considered within the scope of JVPT unless the study has direct relevance to the use of the drug (including toxicants and feed additives) in veterinary species, or that it can be clearly demonstrated that a similar outcome would be expected in vivo. These studies should consider approved or widely used veterinary drugs and/or drugs with broad applicability to veterinary species.
期刊最新文献
The Single-Dose Pharmacokinetics of a Compounded Levetiracetam Formulation and Bioequivalence to a Commercial Formulation in Healthy Dogs. Antimicrobial Pharmacokinetic Studies in Sea Turtles: A Review. Issue Information Pharmacokinetics of Salbutamol in Thoroughbred Horses After a Single Intravenous or Inhaled Administration. Comparative Pharmacokinetics of Intravenous and Subcutaneous Omeprazole in Sheep and Goats.
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