使用 DBS 的肌张力障碍或抽动症患者的妊娠。十四例新病例及文献综述。

IF 2.6 4区医学 Q2 CLINICAL NEUROLOGY Movement Disorders Clinical Practice Pub Date : 2024-11-11 DOI:10.1002/mdc3.14272

Raja Mehanna, Arjun Tarakad, Lisa Yutong Taneff, Erin Furr Stimming

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引用次数: 0

摘要

背景：事实证明，脑深部刺激（DBS）可改善难治性肌张力障碍和抽动秽语综合征（TS）患者的生活质量。由于这些疾病的发病年龄较小，且从 DBS 中获益明显，接受过 DBS 治疗的患者怀孕的情况在临床上越来越常见，尽管目前还缺乏明确的管理指南：我们报告了 14 例肌张力障碍或 TS 和 DBS 患者的新妊娠：文献综述：经查阅文献，之前有 7 篇文章报道了 23 例肌张力障碍或 TS 患者怀孕的情况：根据总共 37 例妊娠的现有数据，DBS 似乎与较差的妊娠结局无关。然而，神经科医生、麻醉师和产科医生之间的精心策划和沟通是关键。应建立 DBS 患者妊娠结局登记册，以便于制定相关指南。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pregnancy in Dystonia or Tourette's Patients with DBS. Fourteen News Cases and a Review of the Literature.

Background: Deep Brain Stimulation (DBS) has been demonstrated to improve quality of life in patients with refractory dystonia and Tourette's syndrome (TS). Because of the young age at onset of these disorders, and the marked benefit from DBS, pregnancy in patients who have received DBS is becoming a more frequent clinical occurrence, although clear management guidelines are lacking.

Cases: We report 14 new pregnancies in patients with dystonia or TS and DBS.

Literature review: Upon review of the literature, 23 pregnancies in patients with dystonia or TS were previously reported in seven articles.

Conclusion: Based on the available data from a total of 37 pregnancies, DBS does not seem associated with worse pregnancy outcome. However, careful planning and communication between neurologist, anesthesiologist and obstetrician are key. A registry on pregnancy outcome in patients with DBS should be generated to facilitate the development of guidelines.

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来源期刊

Movement Disorders Clinical Practice CLINICAL NEUROLOGY-

CiteScore

4.00

自引率

7.50%

发文量

218

期刊介绍： Movement Disorders Clinical Practice- is an online-only journal committed to publishing high quality peer reviewed articles related to clinical aspects of movement disorders which broadly include phenomenology (interesting case/case series/rarities), investigative (for e.g- genetics, imaging), translational (phenotype-genotype or other) and treatment aspects (clinical guidelines, diagnostic and treatment algorithms)