[家族性大肠癌:预防、术后护理和遗传咨询]。

Q4 Medicine Praxis Pub Date : 2024-10-01 DOI:10.23785/PRAXIS.2024.09.002
Kaspar Truninger, Karl Heinimann
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引用次数: 0

摘要

导言:就每年新发病例和癌症死亡人数而言,结肠直肠癌(CRC)是瑞士第三大常见癌症。由于大多数州都开展了有组织的筛查计划,因此有更多人被记录为有阳性家族史。大多数 CRC 患者都有家族遗传史,而遗传性 CRC 则少见得多。CRC 患者的亲属是一个异质性群体,他们的 CRC 风险各不相同。对疾病风险的良好评估可以优化加强预防的收益风险比。这些建议("专家意见陈述")旨在为临床实践提供依据,以便在出现 CRC 家族阳性病史时规划预防保健、监测和人类遗传咨询。
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[Familial occurrence of colorectal cancer: prevention, aftercare and genetic counseling].

Introduction: Colorectal cancer (CRC) is the third most common type of cancer in Switzerland in terms of annual new cases and cancer deaths. Since most cantons have an organized screening program, more people are recorded with a positive family history of CRC. In the majority, the familial form of CRC is present, a hereditary form is much less common. Relatives of patients with CRC are a heterogeneous group whose CRC risk varies. A good assessment of disease risk can optimize the benefit-risk ratio for more intensive prevention. These recommendations («expert opinion statement») are intended to serve as a basis in clinical practice for planning preventative care, monitoring and human genetic counseling in the presence of a family history positive for CRC.

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来源期刊
Praxis
Praxis Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
146
审稿时长
12 weeks
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