东亚儿童嗜酸性粒细胞胃肠道疾病早期诊断和管理的实用概念和策略。

IF 3.2 Q1 PEDIATRICS Clinical and Experimental Pediatrics Pub Date : 2024-11-13 DOI:10.3345/cep.2024.01165
Byung-Ho Choe
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引用次数: 0

摘要

嗜酸性粒细胞胃肠道疾病(EGIDs)正在成为韩国儿科人群的重大问题,并从罕见病症转变为更常见的诊断病症。本综述讨论了 EGID 在儿童和青少年中日益增加的发病率,并强调了其诊断和管理所涉及的复杂性。本综述首先全面探讨了韩国儿童 EGID 的各种临床表现,尤其关注常见的胃肠道症状,如腹痛、腹泻和血便。此外,我们还探讨了肠道外表现,包括生长发育迟缓、营养不良和相关过敏并发症,强调了它们在 EGIDs 临床表现中的重要性。由于 EGID 的症状微妙且与其他胃肠道疾病的症状重叠,因此常常诊断不足。应对这一挑战需要保持高度怀疑,并采用综合诊断方法将 EGID 与功能性胃肠病 (FGID) 及其他炎症性或全身性疾病(如炎症性肠病)区分开来。EGID 的最佳治疗需要多学科协作策略,包括饮食管理、定期监测和有针对性的医疗干预。本综述强调了积极主动地对患者和护理人员进行教育和定期随访对改善患儿长期预后的重要性。提高医疗保健提供者的认识和为家庭提供更好的教育资源,对于早期识别和有效管理儿科 EGID 患者至关重要。
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Practical Concepts and strategies for early diagnosis and management of eosinophilic gastrointestinal disorders in East-Asian children.

Eosinophilic gastrointestinal disorders (EGIDs) are emerging as significant concerns in the Korean pediatric population and transitioning from rare to more commonly diagnosed conditions. This review discusses the increasing prevalence of EGID among children and adolescents and highlights the complexities involved in its diagnosis and management. This review begins with a thorough examination of the diverse clinical presentations of EGIDs in Korean children, with a special focus on common gastrointestinal symptoms such as abdominal pain, diarrhea, and bloody stool. Additionally, we explored extraintestinal manifestations, including growth failure, malnutrition, and associated allergic comorbidities, highlighting their importance in the clinical landscape of EGIDs. Because of its subtle and overlapping symptoms with those of other gastrointestinal disorders, EGID is frequently underdiagnosed. Addressing this challenge requires maintaining a high index of suspicion and employing a comprehensive diagnostic approach to differentiating EGID from functional gastrointestinal disorders (FGIDs) and other inflammatory or systemic diseases such as inflammatory bowel disease. The optimal management of EGID requires a collaborative multidisciplinary strategy that includes dietary management, regular monitoring, and tailored medical interventions. This review emphasizes the importance of proactive patient and caregiver education and regular follow-ups to improve long-term outcomes in affected children. Enhanced awareness among healthcare providers and better educational resources for families are critical for the early identification and effective management of EGID among pediatric patients.

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来源期刊
CiteScore
8.00
自引率
2.40%
发文量
88
审稿时长
60 weeks
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