[译文]糖尿病足患者轻微截肢后的再截肢率,一项横断面研究。

C A Sánchez Correa, I Briceño Sanín, J J Bautista Valencia, M E Niño, J Robledo Quijano
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引用次数: 0

摘要

导言:据报道,糖尿病足再截肢的发生率各不相同,轻微截肢的风险因素尚不明确。本研究旨在确定糖尿病足轻微截肢后再次截肢的发生率,并评估造成这种结果的相关因素:方法:在两家医院开展横断面研究。方法:在两家医院开展横断面研究,纳入因糖尿病足溃疡住院并需要进行轻微截肢的患者。研究对所有变量进行了描述性分析,并对患病率比(PR)和多变量逻辑回归进行了分析:结果:15 年间,患病率为 48%。脚趾是最常见的需要再次截肢的轻微截肢部位,膝关节以上截肢是最常见的再次截肢部位(45%)。PR与再截肢风险相关的变量有:吸烟史(PR 1.32,CI 95%:1.02-1.67,P = 0.03)、多普勒血管闭塞(PR 1.47,CI 95%:1.11-1.73,P = 0.01)、血管再通(PR 1.73,CI 95%:1.31-2.14,P = 0.00002)、Wagner>3(PR 1.75,CI 95%:1.16-1.84,P = 0.01)和白细胞>11000(PR 1.39,CI 95%:1.07-1.68,P = 0.01)。白细胞>11,000、Wagner>3、多普勒血管闭塞和血管再通是预测结果的最佳变量。此外,白细胞增多是预测再狭窄的最佳变量(OR 2.4,CI 95%:1.1-5.6,P = 0.04):再次截肢率为48%。脚趾是较常需要再次截肢的小截肢部位,膝关节以上是最常发生再次截肢的部位。再次截肢的风险与血管损伤和感染相关。
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[Translated article] Reamputation prevalence after minor feet amputations in patients with diabetic foot: A cross sectional study.

Introduction: Reported prevalence for reamputation in diabetic foot is diverse, risk factors are not clear for minor amputations. This study aims to determine the prevalence for reamputation in diabetic foot from minor amputations and to evaluate associated factors for such outcome.

Methods: Cross sectional study developed in 2 hospitals. Patients hospitalized for diabetic foot ulcer requiring a minor amputation were included. A descriptive analysis of all variables is presented, as well as prevalence ratios (PR) and a multivariate logistic regression.

Results: The prevalence was of 48% for 15 years. Toes were the most frequent minor amputation that required reamputation and above the knee amputation was the most frequent reamputation level (45%). Variables whose PR was associated to reamputation risk were: smoking history (PR 1.32, CI 95%: 1.02-1.67, p=0.03), vascular occlusion in doppler (PR 1.47, CI 95%: 1.11-1.73, p=0.01), revascularization (PR 1.73, CI 95%: 1.31-2.14, p=0.00002), Wagner>3 (PR 1.75, CI 95%: 1.16-1.84, p=0.01) and leucocytosis>11,000 (PR 1.39, CI 95%: 1.07-1.68, p=0.01). Leucocytosis>11,000, Wagner>3, vascular occlusion in doppler and revascularization were the variables that best predicted the outcome. Furthermore, leucocytosis was the best variable for predicting reamputation (OR 2.4, CI 95%: 1.1-5.6, p=0.04).

Conclusions: Reamputation prevalence was 48%. The toes were the minor amputation more frequently requiring reamputation and above the knee was the most frequent reamputation level. Risk for reamputation was associated with variables related to vascular compromise and infection.

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自引率
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156
审稿时长
51 weeks
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