用于葡萄膜黑色素瘤近距离放射治疗的缺口眼斑 "假人 "的新型 3D 打印方法。

Brachytherapy Pub Date : 2025-01-01 Epub Date: 2024-11-13 DOI:10.1016/j.brachy.2024.09.002
Firas Mourtada, Sara Belko, Rachel Monane, Robert Pugliese, Lydia Komarnicky-Kocher, Sara E Lally, Wentao Wang, Carol L Shields, Jacqueline Emrich
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引用次数: 0

摘要

目的:眼部肿瘤外科医生在为眼部黑色素瘤近距离放射治疗插入放射性斑块之前,缝合预置是一个关键步骤。我们报告了一种新颖的三维打印方法,该方法利用内部三维打印技术为 22 毫米带凹口的金斑块创建了一个定制的 "假 "斑块涂抹器:方法:创建了一个计算机辅助设计(CAD)文件,复制了一个大量使用的金斑块,该斑块不再有令人满意的 "假 "斑块。该文件被导出为三维文件(曲面细分语言,STL),并使用 Formlabs 的 PreForm 打印软件进行准备。三维打印的假人在打印机上的方向是在与患者外部巩膜接触的表面上没有杯状或支撑物。假体是在 Formlabs Form-3 三维打印机上用 FormLabs BioMed Clear V1 打印出来的。打印完成后,假体在异丙醇中进行处理,并按照制造商的说明进行固化。使用旋转工具对假人进行抛光,以提高透明度。为确保假人的完整性,还进行了化学和灭菌循环测试:结果:共打印了四块 "假 "牌匾。使用数字卡尺验证了 3D 打印的 "假 "牌匾尺寸与缺口牌匾的尺寸相差在 0.5 毫米以内。抛光过程为手术室中的眼斑手术提供了可接受的不透明度。在所进行的化学和灭菌循环测试中,没有观察到有影响的褪色或材料变化:3D打印技术可以使用透明、生物相容性好、化学惰性的材料制作出适合人体使用的定制眼斑假体。这种能力为患者特定的卫生学提供了一个额外的层面。
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A novel 3D printing method for a notched eye plaque "dummy" for uveal melanoma brachytherapy.

Purpose: Suture preplacement by the ocular oncology surgeon is a critical step before inserting a radioactive plaque for ocular melanoma brachytherapy. We report on a novel 3D-printing method to create a custom "dummy" plaque applicator for the 22 mm notched gold plaque using in-house 3D-printing.

Methods: A computer-aided design (CAD) file was created replicating a heavily used gold plaque that no longer has a satisfactory "dummy" plaque. The file was exported as a 3D file (surface tessellation language, STL) and prepared using Formlabs' PreForm print software. The 3D-printed dummies were oriented on the printer to have no cups or supports on the surfaces that would come in contact with the patient's external sclera. The dummies were printed in FormLabs BioMed Clear V1 on a Formlabs Form-3 3D printer. Postprinting, the dummies were processed in isopropyl alcohol and cured according to manufacturer instructions. They were polished utilizing a rotary tool to improve transparency. Chemical and sterilization cycle tests were performed to ensure dummy integrity.

Results: Four "dummy" plaques were printed. The 3D-printed "dummy" dimensions were verified to be within 0.5-mm of the notched plaque using digital calipers. The polishing process created acceptable light opacity for the eye plaque procedure in the operating room. No impactful discoloration or material change was observed during the chemical and sterilization cycle tests performed.

Conclusions: 3D printing can produce custom eye plaque dummies using transparent, biocompatible, chemically inert materials suitable for human use. This capability introduces an additional layer of patient-specific hygienics.

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