使用 TOPAS 对用于 HDR 近距离放射治疗的 GammaMed Plus 192Ir 放射源进行蒙特卡罗建模和剂量学验证。

IF 1.6 3区工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Applied Radiation and Isotopes Pub Date : 2024-11-06 DOI:10.1016/j.apradiso.2024.111584

Ravindra Shende , S.J. Dhoble , Umesh Gayake

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引用次数: 0

摘要

研究旨在使用 TOPAS 中的 Geant4 代码对用于高剂量率近距离放射治疗的 GammaMed Plus 192Ir 源进行蒙特卡罗（MC）建模和剂量学验证。研究调查了用于近距离放射剂量计算的几个 TG-43 引导剂量学参数。结果发现，模拟数据与已公布的数据非常吻合。模拟的 MC 数据集可作为参考，并输入治疗计划系统 (TPS) 以验证近距离治疗剂量计算。目前的近距离放射源 MC 建模可用于进一步的特定患者 MC 模拟研究。

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Monte Carlo modeling and dosimetric validation of GammaMed Plus 192Ir source for HDR brachytherapy application using TOPAS

Study aimed at Monte Carlo (MC) modeling and dosimetric validation of GammaMed Plus ¹⁹²Ir source for high dose rate brachytherapy using Geant4 code in TOPAS. Study investigated the several TG-43 guided dosimetric parameters for brachytherapy dose calculation. The excellent agreement was found between simulated and published data. The simulated MC dataset can be served as reference and fed into Treatment planning system (TPS) to verify brachytherapy dose calculation. Present MC modeling of brachytherapy source can be availed in further patient specific studies involving MC simulation.

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来源期刊

Applied Radiation and Isotopes 工程技术-核科学技术

CiteScore

3.00

自引率

12.50%

发文量

406

审稿时长

13.5 months

期刊介绍： Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.