难治性和超难治性癫痫状态:治疗方案和预后。

IF 2.4 4区 医学 Q2 CLINICAL NEUROLOGY Neurologic Clinics Pub Date : 2024-10-15 DOI:10.1016/j.ncl.2024.07.002
Andrea O. Rossetti MD
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引用次数: 0

摘要

在癫痫状态(SE)患者中,潜在的生物背景是预后的主要变量。建议迅速实施治疗方案,包括使用足量的苯二氮卓类药物,然后静脉注射抗癫痫药物。如果出现难治性 SE,应在昏迷中对全身抽搐和非抽搐性 SE 使用全身麻醉剂,而对局灶性 SE 患者则应进一步尝试使用非镇静抗癫痫药物。应及早考虑对超级难治性 SE 患者使用生酮饮食和/或氯胺酮,对新发难治性 SE/发热诱发难治性癫痫综合征患者使用免疫疗法。心脏骤停后 SE 的药物治疗应以多模式预后结果为导向。
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来源期刊
Neurologic Clinics
Neurologic Clinics 医学-临床神经学
CiteScore
5.00
自引率
4.20%
发文量
92
审稿时长
6-12 weeks
期刊介绍: Targeted toward those in the fields of neurology, family medicine, otolaryngology, and pediatrics, Neurologic Clinics offers a broad view of current practice, as well as the evidence to support it. Published quarterly — in February, May, August, and November — each issue focuses on a single topic neurology, including hearing loss, cholesteatoma, rhinology, anosmia, dysphagia, and pediatric-specific ENT.
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