基于 Azadirachta indica 的草药漱口水在治疗牙齿过敏症方面的临床疗效。

IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pakistan Journal of Medical Sciences Pub Date : 2024-11-01 DOI:10.12669/pjms.40.10.9826
Afsheen Mansoor, Emaan Mansoor, Nehal Amir, Khadim Hussain
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引用次数: 0

摘要

目的评估以 Azadirachta indica 为基础的草药漱口水治疗患者牙齿敏感的效果:这项单盲临床试验于 2023 年 2 月 1 日至 2023 年 4 月 30 日在伊斯兰堡沙希德-祖利菲卡尔-阿里-布托医科大学牙科学院进行。在这项干预性研究中,有 120 名参与者出现了临床可见的侵蚀、磨损或衰退迹象。使用视觉模拟评分(VAS)工具调查这些患者的牙齿敏感度。在不使用含 Azadirachta indica 的草本漱口水的情况下,将这些患者的牙齿暴露在牙科设备上的三重注射器中,在 23±30ºC 之间以 psi-30.0 的压力吹冷风,持续一秒钟,计算出牙齿敏感度的 VAS 值。随后,向这些患者提供这种草药漱口水,并建议他们在一个月内每天使用两次。一个月后,再次用 VAS 测定患者的牙齿敏感度。数据采用配对 T 检验进行分析,置信度为 95%,显著性 < 0.05:使用草本漱口水前,患者牙齿敏感度的 VAS 平均值较高,为 55.43% ± 12.04,而使用草本漱口水一个月后,其平均值降至 35.38% ± 11.62,具有统计学意义(P 值=0.001)。一个月后,患者的牙齿敏感度降低了近 20.05%:结论:使用 Azadirachta indica 草本漱口水一个月后,其功效足以降低患者的牙齿敏感度。
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Clinical efficacy of Azadirachta indica based herbal mouthwash in treating the hypersensitivity of teeth.

Objective: To evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat tooth sensitivity in patients.

Method: This single-blinded clinical trial was performed at School of dentistry, Shaheed Zulfiqar Ali Bhutto Medial University, Islamabad from 1st February, 2023 to 30th April, 2023. In this interventional study incorporated 120 participants with clinically visible signs of erosion, abrasion or recession. Visual Analog Scoring (VAS) Tool was used to investigate tooth sensitivity in these patients. Values of VAS for tooth sensitivity was calculated by exposing teeth of these patients to cold air blasting with triple syringe attached to dental unit at psi-30.0 pressure between 23±30ºC for duration of one second without using Azadirachta indica based Herbal mouthwash. Later on, these patients were provided with this Herbal mouthwash and its usage was recommended twice a day for one month. After One month, tooth sensitivity of patients was determined by VAS again. Data was analyzed by Paired T-test at 95% confidence and significance < 0.05.

Results: VAS mean value for tooth sensitivity of patients before using Azadirachta indica based Herbal mouthwash was higher and found to be 55.43% ± 12.04 whereas its mean value after using Herbal mouthwash for one month reduced to 35.38% ± 11.62 which was statistically significant (p value=0.001). Reduction in tooth sensitivity of patients was almost 20.05% just after one month.

Conclusion: Azadirachta indica based Herbal mouthwash was potent enough to reduce the tooth sensitivity in patients after one month of its usage.

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来源期刊
Pakistan Journal of Medical Sciences
Pakistan Journal of Medical Sciences 医学-医学:内科
CiteScore
4.10
自引率
9.10%
发文量
363
审稿时长
3-6 weeks
期刊介绍: It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad. Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.
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