小儿阿片类药物使用相关神经毒性伴小脑水肿：Galen 静脉动脉瘤治疗后的 POUNCE 综合征病例。

IF 1 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of the Belgian Society of Radiology Pub Date : 2024-11-14 eCollection Date: 2024-01-01 DOI:10.5334/jbsr.3786

Maxime Goldfinger

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引用次数: 0

摘要

我们报告了一例 4 岁患儿的病例，该患儿在接受介入手术治疗 Galen 静脉动脉瘤的麻醉过程中服用了阿片类药物，随后神经功能迅速衰退。脑磁共振成像（MRI）显示小脑半球和脑干出现明显的细胞毒性水肿，表明阿片类药物诱发了神经毒性。两周后进行的随访核磁共振成像显示，小脑和脑干严重萎缩，细胞毒性水肿导致的肿块效应减弱。教学要点小儿阿片类药物使用相关神经毒性伴小脑水肿（POUNCE）综合征是一种罕见病，其特征是小脑水肿，可在小儿患者使用阿片类药物后通过核磁共振成像发现。

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Pediatric Opioid‑Use‑Associated Neurotoxicity with Cerebellar Edema: A Case of POUNCE Syndrome Following Vein of Galen Aneurysm Treatment.

We report the case of a 4‑year‑old child who experienced rapid neurological decline following opioid administration during anesthesia for an interventional procedure to treat a vein of Galen aneurysm. Cerebral magnetic resonance imaging (MRI) revealed marked cytotoxic edema in both cerebellar hemispheres and the brainstem, indicative of opioid‑induced neurotoxicity. A follow‑up MRI, performed 2 weeks later, showed profound cerebellar and brainstem atrophy and showed reduction in mass effect due to cytotoxic edema. Teaching point: Pediatric opioid‑use‑associated neurotoxicity with cerebellar edema (POUNCE) syndrome is a rare condition, characterized by cerebellar edema as a hallmark feature, which can be identified on MRI in pediatric patients following opioid use.

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来源期刊

Journal of the Belgian Society of Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

0.70

自引率

5.00%

发文量

期刊介绍： The purpose of the Journal of the Belgian Society of Radiology is the publication of articles dealing with diagnostic and interventional radiology, related imaging techniques, allied sciences, and continuing education.

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