利用光学相干断层扫描进行视网膜疾病分类的轻量级模型

IF 4.9 2区 医学 Q1 ENGINEERING, BIOMEDICAL Biomedical Signal Processing and Control Pub Date : 2024-11-17 DOI:10.1016/j.bspc.2024.107146
Hongyi Pan , Jingpeng Miao , Jie Yu , Jingran Dong , Mingming Zhang , Xiaobing Wang , Jihong Feng
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引用次数: 0

摘要

老年性黄斑变性和糖尿病性黄斑水肿等视网膜疾病如果得不到及时诊断和治疗,将导致不可逆转的失明。光学相干断层扫描(OCT)具有非接触、非侵入性成像的特点,已被广泛用于检测视网膜疾病。由于眼科医疗资源的匮乏,视网膜 OCT 图像的自动分析和诊断需要计算机辅助诊断算法。在这项研究中,我们提出了一种整合了卷积神经网络(CNN)和变换器的轻量级视网膜 OCT 图像分类模型,只需少量模型参数即可对各种视网膜疾病进行分类。CNN 提取的局部病变特征可通过 Transformer 与整个 OCT 图像进行编码,从而提高分类能力。我们的模型还集成了卷积块注意力模块,以增强表征能力。与几种经典模型相比,我们的模型在 OCT-C8 数据集上以最少的参数数量和最少的图像预测时间达到了最佳准确率 0.9800 和召回率 0.9799。此外,在 OCT2017 数据集上,我们的模型除几乎与另一个模型持平外,在准确度、精确度、召回率、特异性和 F1 分数上的平均值分别为 0.9985、0.9970、0.9970、0.9990 和 0.9970,优于四个最先进的模型。同时,我们的模型参数数也减少到了 1.28 M,图像的平均预测时间仅为 2.5 ms。
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A lightweight model for the retinal disease classification using optical coherence tomography
Retinal diseases such as age-related macular degeneration and diabetic macular edema will lead to irreversible blindness without timely diagnosis and treatment. Optical coherence tomography (OCT) has been widely utilized to detect retinal diseases because of its non-contact and non-invasive imaging peculiarities. Due to the lack of ophthalmic medical resources, automatic analyzing and diagnosing retinal OCT images is necessary with computer-aided diagnosis algorithms. In this study, we propose a lightweight retinal OCT image classification model integrating convolutional neural network (CNN) and Transformer to classify various retinal diseases with few parameters of the model. Local lesion features extracted by CNN can be encoded with the whole OCT image through the Transformer, which improves the classification ability. A convolutional block attention module is also integrated into our model to enhance the representational power. Compared with several classical models, our model achieves the best accuracy of 0.9800 and recall of 0.9799 with the least number of parameters and prediction time for an image on the OCT-C8 dataset. Moreover, on the OCT2017 dataset, our model outperforms the four state-of-the-art models except almost equal to another, achieving an average accuracy, precision, recall, specificity and F1-score of 0.9985, 0.9970, 0.9970, 0.9990, and 0.9970. Simultaneously, the number of parameters of our model has been reduced to just 1.28 M, and the average prediction time for an image is only 2.5 ms.
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来源期刊
Biomedical Signal Processing and Control
Biomedical Signal Processing and Control 工程技术-工程:生物医学
CiteScore
9.80
自引率
13.70%
发文量
822
审稿时长
4 months
期刊介绍: Biomedical Signal Processing and Control aims to provide a cross-disciplinary international forum for the interchange of information on research in the measurement and analysis of signals and images in clinical medicine and the biological sciences. Emphasis is placed on contributions dealing with the practical, applications-led research on the use of methods and devices in clinical diagnosis, patient monitoring and management. Biomedical Signal Processing and Control reflects the main areas in which these methods are being used and developed at the interface of both engineering and clinical science. The scope of the journal is defined to include relevant review papers, technical notes, short communications and letters. Tutorial papers and special issues will also be published.
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