胸部放疗中一个新的危险解剖区域的简要报告：从发现到实施

IF 3 Q2 ONCOLOGY JTO Clinical and Research Reports Pub Date : 2024-10-18 DOI:10.1016/j.jtocrr.2024.100742

Kathryn Banfill PhD, FRCR , Thomas Marchant PhD , Alan McWilliam PhD , Joseph Wood PhD , Matthias Schmitt MD, PhD , Azadeh Abravan PhD , Gareth Price PhD , Marcel van Herk PhD , Corinne Faivre-Finn PhD, FRCR

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摘要

增加特定心脏结构的放疗剂量与心脏事件和过早死亡有关。我们根据基于图像的数据挖掘研究，通过共识意见定义了一个新的放疗风险心脏解剖区域。心脏避开区域包括上腔静脉、右心房、主动脉根部、左冠状动脉主干、左前降支和右冠状动脉近段。我们描述了心脏避开区域的轮廓图集，以方便实施。

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Brief Report of a New Anatomical Region at Risk in Thoracic Radiotherapy: From Discovery to Implementation

Increasing radiotherapy dose to select cardiac structures is associated with cardiac events and premature death. Previous studies have found a dose–response relationship for structures at the base of the heart.

We have defined a new cardiac anatomical region at risk for radiotherapy by consensus opinion, based on image-based data-mining studies. The cardiac avoidance area comprises the superior vena cava, right atrium, aortic root, left main coronary artery, and proximal segments of the left anterior descending and right coronary arteries. We describe a contouring atlas for the cardiac avoidance area to facilitate implementation.

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