咳嗽变异性哮喘：临床特征、诊断和病理生理学综述。

IF 8.2 1区医学 Q1 ALLERGY Journal of Allergy and Clinical Immunology-In Practice Pub Date : 2024-11-16 DOI:10.1016/j.jaip.2024.11.005

Joshua K Cox, Richard Lockey, Juan Carlos Cardet

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引用次数: 0

摘要

慢性咳嗽是引发医疗护理的最常见症状之一。咳嗽变异性哮喘（CVA）是一种以咳嗽为主要症状的哮喘亚型，不伴有喘息、胸闷或呼吸困难。它是慢性咳嗽的一个重要原因，估计占病例的 25% 至 42%，但由于识别延迟和诊断检测的误区，很可能诊断不足。早期识别和治疗可以降低发病率，并延缓其发展为更典型的哮喘。本综述详细介绍了 CVA 的临床特征、诊断、病理生理学和治疗方法，并将其与典型哮喘（CA）和其他原因引起的慢性咳嗽进行了对比。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cough Variant Asthma: A Review of Clinical Characteristics, Diagnosis, and Pathophysiology.

Chronic cough is among the most common symptoms prompting medical care. Cough variant asthma (CVA) is an asthma subset where cough is the primary symptom, without wheezing, chest tightness, or dyspnea. It is an important cause of chronic cough, estimated to account for 25% to 42% of cases, but likely underdiagnosed due to delayed recognition and pitfalls of diagnostic testing. Early recognition and treatment can reduce morbidity and delay its progression to more typical asthma. This review details the clinical characteristics, diagnosis, pathophysiology, and treatment of CVA and contrasts it with classic asthma (CA) and other causes of chronic cough.

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来源期刊

Journal of Allergy and Clinical Immunology-In Practice ALLERGYIMMUNOLOGY-IMMUNOLOGY

CiteScore

11.10

自引率

9.60%

发文量

683

审稿时长

50 days

期刊介绍： JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.