Dana Hyassat, Ala'a Al-Refai, Yousef S Khader, Malik E Juweid, Saja AlSharaydeh, Nadera Layyous, Husam Aljabiry, Ahmad AlDurgham, Laith Z Baqain, Joud Abu Summaqa, Rana Al-Shimi, Fatima Mohammad Atieh, Awn Mahasneh, Shaker Alaraj, Alanoud Al-Wakfi, Omar Mahafza, Mohammad El-Khateeb, Kamel Ajlouni
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引用次数: 0
摘要
代谢综合征是全球主要的公共卫生问题,也是 2 型糖尿病(T2DM)患者罹患心血管疾病的独立预测因素。本研究旨在确定约旦 T2DM 患者中代谢综合征的发病率及其各个组成部分。研究在约旦国家糖尿病、内分泌学和遗传学中心的 T2DM 患者中进行了横断面设计。通过结构化问卷和从病历中提取的临床数据收集数据。采用美国国家胆固醇教育计划-成人治疗小组 III(ATP III)和国际糖尿病联盟(IDF)的诊断标准来定义代谢综合征。在 1017 名年龄介于 22 岁至 90 岁之间的参与者中,IDF 定义的代谢综合征总患病率为 84.2%(男性和女性的患病率分别为 72.5% 和 96.2%)。根据 ATP III 标准,总患病率为 79.1%(男性和女性分别为 77.4% 和 80.8%)。无论采用哪种定义,年龄增长、女性性别、不坚持饮食疗法、久坐不动的生活方式或体力活动不足以及糖尿病病程≥10 年都与代谢综合征发生几率的增加有显著关联。目前的吸烟状况和心血管疾病家族史与 ATP III 定义的代谢综合征发生几率增加有明显关联。在约旦的 T2DM 患者中,代谢综合征的发病率非常高。在这些患者中,代谢综合征的主要可改变风险因素包括不遵守饮食方案、体育锻炼不足、超重/肥胖和吸烟。建议医疗服务提供者向患者宣传坚持体育锻炼、戒烟和坚持饮食疗法的重要性。
Metabolic syndrome among patients with type 2 diabetes in Jordan: A cross-sectional study.
Metabolic syndrome is a major public health problem worldwide and an independent predictor of cardiovascular disease in patients with type 2 diabetes (T2DM). This study aimed to determine the prevalence of metabolic syndrome and its individual components among Jordanian patients with T2DM. A cross-sectional design was conducted among T2DM patients at the National Center for Diabetes, Endocrinology and Genetics in Jordan. Data were collected using a structured questionnaire and clinical data extracted from medical records. The National Cholesterol Education Program-Adult Treatment Panel III (ATP III) and International Diabetes Federation (IDF) diagnostic criteria were used to define metabolic syndrome. Among 1017 participants aged between 22 and 90 years, the overall prevalence of IDF defined metabolic syndrome was 84.2% (72.5% and 96.2% among males and females, respectively). Using ATP III criteria, overall prevalence was 79.1% (77.4% and 80.8% among males and females, respectively). Advancing age, female gender, nonadherence to a diet regimen, sedentary lifestyle or insufficient physical activity, and duration of diabetes ≥10 years were significantly associated with increased odds of metabolic syndrome, regardless of the definition used. Current smoking status and family history of cardiovascular diseases were significantly associated with increased likelihood of ATP III defined metabolic syndrome. The prevalence of metabolic syndrome among Jordanian patients with T2DM is extremely high. The main modifiable risk factors of metabolic syndrome among these patients include nonadherence to a diet regimen, insufficient physical activity, being overweight/obese and smoking. It is recommended that healthcare providers counsel patients on the importance of maintaining physical activity, smoking cessation, and adherence to a diet regimen.
期刊介绍:
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