儿科急性甲型肝炎感染引发的罕见格林-巴利综合征:病例报告和文献综述。

IF 2.3 4区 医学 Q3 NEUROSCIENCES Journal of NeuroVirology Pub Date : 2024-11-19 DOI:10.1007/s13365-024-01237-4
Erfan Shahabinejad, Amirreza Shakoeizadeh, Alireza Vakilian, Seyyed Mohammad Alipour, Fatemeh Jalali, Faezeh Ebrahimi, Narges Mashyekhi
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引用次数: 0

摘要

格林-巴利综合征(Guillain-Barre Syndrome,GBS)是一种罕见但严重的神经系统疾病,以急性弛缓性麻痹和肢体瘫痪为特征,通常发生在感染性疾病之后。本病例报告描述了一名原本健康的 9 岁男孩在急性甲型肝炎感染后出现 GBS。经临床和电生理学检查证实,患者表现为快速进展性乏力、上行性麻痹和肢体瘫痪。结果与急性运动性轴索神经病的 GBS 亚组一致。接受静脉注射免疫球蛋白(IVIG)治疗后,病情逐渐好转,这凸显了早期识别和干预的重要性。本报告回顾了有关 GBS 与甲型肝炎之间关联的现有文献,强调了此类病例在儿科人群中的罕见性。报告旨在提高临床医生对甲型肝炎潜在并发症的认识,强调及时诊断和治疗的必要性,以改善类似病例的治疗效果。报告强调需要及时诊断和治疗,以改善类似病例的治疗效果。
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A rare kind of Guillain-Barre syndrome triggered by acute hepatitis A infection in a pediatric patient: a case report and review of literature.

Guillain-Barre Syndrome (GBS) is a rare but serious neurological disorder characterized by acute flaccid paralysis and areflexia, usually after an infectious disease. This case report describes a previously healthy 9-year-old boy who developed GBS following an acute hepatitis A infection. The patient presented with rapidly progressive weakness, ascending paralysis, and areflexia, confirmed by clinical and electrophysiological findings. Results were consistent with the GBS subgroup of Acute Motor Axonal Neuropathy. Treatment with intravenous immunoglobulin (IVIG) led to gradual improvement, highlighting the importance of early recognition and intervention. This report reviews the current literature on the association between GBS and hepatitis A, emphasizing the rarity of such cases in pediatric populations. The report aims to raise awareness among clinicians about this potential complication of hepatitis A, underscoring the need for prompt diagnosis and treatment to improve outcomes in similar cases. The report emphasizes the need for prompt diagnosis and treatment to improve outcomes in similar cases.

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来源期刊
Journal of NeuroVirology
Journal of NeuroVirology 医学-病毒学
CiteScore
6.60
自引率
3.10%
发文量
77
审稿时长
6-12 weeks
期刊介绍: The Journal of NeuroVirology (JNV) provides a unique platform for the publication of high-quality basic science and clinical studies on the molecular biology and pathogenesis of viral infections of the nervous system, and for reporting on the development of novel therapeutic strategies using neurotropic viral vectors. The Journal also emphasizes publication of non-viral infections that affect the central nervous system. The Journal publishes original research articles, reviews, case reports, coverage of various scientific meetings, along with supplements and special issues on selected subjects. The Journal is currently accepting submissions of original work from the following basic and clinical research areas: Aging & Neurodegeneration, Apoptosis, CNS Signal Transduction, Emerging CNS Infections, Molecular Virology, Neural-Immune Interaction, Novel Diagnostics, Novel Therapeutics, Stem Cell Biology, Transmissable Encephalopathies/Prion, Vaccine Development, Viral Genomics, Viral Neurooncology, Viral Neurochemistry, Viral Neuroimmunology, Viral Neuropharmacology.
期刊最新文献
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