米诺环素诱发的全身性 II 型色素沉着：病例报告

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL SAGE Open Medical Case Reports Pub Date : 2024-11-19 eCollection Date: 2024-01-01 DOI:10.1177/2050313X241297214

Wumei Zhao, Haijing Fu, Tianyi Xu, Shi-Jun Shan

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引用次数: 0

摘要

米诺环素诱发的色素沉着是一种罕见的皮肤病，主要影响皮肤和甲状腺、口腔粘膜、指甲、牙齿、骨骼和巩膜，导致这些部位出现灰蓝色色素沉着。早期识别、停药和激光治疗是控制这种疾病的关键。我们报告了一例 72 岁中国妇女的病例，她在接受米诺环素治疗寻常型丘疹性荨麻疹 1 年后，出现了弥漫性蓝褐色色素沉着。组织学检查显示，皮损处的真皮层中存在多个含有色素的巨噬细胞和游离色素。根据我们的文献综述，与之前报道的中国患者相比，本病例的全身皮肤受累非常罕见。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Generalized type II minocycline-induced pigmentation: A case report.

Minocycline-induced pigmentation is a rare dermatological condition that primarily affects the skin and thyroid gland, oral mucosa, nails, teeth, bones, and sclera leading to grayish-blue pigmentation in these areas. Early identification, discontinuation of the drug, and laser treatment are crucial in managing this condition. We reported a case involving a 72-year-old Chinese woman who developed diffuse blue-brown pigmentation after 1 year of minocycline treatment for pemphigus vulgaris. Histological examination revealed multiple pigment-laden macrophages and free pigment in the dermis at the skin lesions. According to our review of the literatures, the generalized skin involvement made our case very rare in comparison with those previously reported of Chinese patients.

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来源期刊

SAGE Open Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.60

自引率

0.00%

发文量

320

审稿时长

8 weeks

期刊介绍： SAGE Open Medical Case Reports (indexed in PubMed Central) is a peer reviewed, open access journal. It aims to provide a publication home for short case reports and case series, which often do not find a place in traditional primary research journals, but provide key insights into real medical cases that are essential for physicians, and may ultimately help to improve patient outcomes. SAGE Open Medical Case Reports does not limit content due to page budgets or thematic significance. Papers are subject to rigorous peer review and are selected on the basis of whether the research is sound and deserves publication. By virtue of not restricting papers to a narrow discipline, SAGE Open Medical Case Reports facilitates the discovery of the connections between papers, whether within or between disciplines. Case reports can span the full spectrum of medicine across the health sciences in the broadest sense, including: Allergy/Immunology Anaesthesia/Pain Cardiovascular Critical Care/ Emergency Medicine Dentistry Dermatology Diabetes/Endocrinology Epidemiology/Public Health Gastroenterology/Hepatology Geriatrics/Gerontology Haematology Infectious Diseases Mental Health/Psychiatry Nephrology Neurology Nursing Obstetrics/Gynaecology Oncology Ophthalmology Orthopaedics/Rehabilitation/Occupational Therapy Otolaryngology Palliative Medicine Pathology Pharmacoeconomics/health economics Pharmacoepidemiology/Drug safety Psychopharmacology Radiology Respiratory Medicine Rheumatology/ Clinical Immunology Sports Medicine Surgery Toxicology Urology Women''s Health.