{"title":"儿童癫痫状态:风险因素与临床评估。","authors":"Asma Marzouk, Ilyes Ben Yahia, Meriem Lajili, Nour Jlaila, Rahma Thebti, Asma Bouaziz","doi":"10.62438/tunismed.v102i11.4493","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction and aim: </strong>Status epilepticus (SE) in children is a critical condition that can be life-threatening. The objective of this study was to identify factors associated with the occurrence of SE after a first convulsive seizure in children.</p><p><strong>Methods: </strong>A retrospective study was conducted at the pediatric department of BEN AROUS regional hospital between January 2015 and December 2019.</p><p><strong>Results: </strong>A total of 300 patients admitted for a first epileptic seizure were included in this analysis. The mean age of the patients was 33 months. Seizures were generalized in 92.7%, with tonic-clonic seizures being the most common (54.8%). SE was diagnosed as inaugural in 29% of cases. Abnormalities in EEG were observed in 36.5% of cases, while MRI revealed abnormal results in 32.8% of patients. Factors associated with a risk of SE recurrence were age younger than 1 year (p = 0.003), neuromotor retardation (p = 0.001), EEG abnormalities (p < 0.001), MRI abnormalities (p = 0.001), and abrupte discontinuation of antiepileptic treatment (p < 0.001). Simple febrile seizure was identified as a protective factor (p = 0.038).</p><p><strong>Conclusion: </strong>The study identified that age under 1 year, neuromotor delay, and abnormalities in EEG and MRI are significant risk factors for the recurrence of status epilepticus after a first epileptic seizure in children. These findings suggest targeted preventive strategies to improve the management and prognosis of these patients.</p>","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"102 11","pages":"899-902"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Status Epilepticus in Children: Risk Factors and Clinical Evaluation.\",\"authors\":\"Asma Marzouk, Ilyes Ben Yahia, Meriem Lajili, Nour Jlaila, Rahma Thebti, Asma Bouaziz\",\"doi\":\"10.62438/tunismed.v102i11.4493\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction and aim: </strong>Status epilepticus (SE) in children is a critical condition that can be life-threatening. The objective of this study was to identify factors associated with the occurrence of SE after a first convulsive seizure in children.</p><p><strong>Methods: </strong>A retrospective study was conducted at the pediatric department of BEN AROUS regional hospital between January 2015 and December 2019.</p><p><strong>Results: </strong>A total of 300 patients admitted for a first epileptic seizure were included in this analysis. The mean age of the patients was 33 months. Seizures were generalized in 92.7%, with tonic-clonic seizures being the most common (54.8%). SE was diagnosed as inaugural in 29% of cases. Abnormalities in EEG were observed in 36.5% of cases, while MRI revealed abnormal results in 32.8% of patients. Factors associated with a risk of SE recurrence were age younger than 1 year (p = 0.003), neuromotor retardation (p = 0.001), EEG abnormalities (p < 0.001), MRI abnormalities (p = 0.001), and abrupte discontinuation of antiepileptic treatment (p < 0.001). Simple febrile seizure was identified as a protective factor (p = 0.038).</p><p><strong>Conclusion: </strong>The study identified that age under 1 year, neuromotor delay, and abnormalities in EEG and MRI are significant risk factors for the recurrence of status epilepticus after a first epileptic seizure in children. These findings suggest targeted preventive strategies to improve the management and prognosis of these patients.</p>\",\"PeriodicalId\":38818,\"journal\":{\"name\":\"Tunisie Medicale\",\"volume\":\"102 11\",\"pages\":\"899-902\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tunisie Medicale\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.62438/tunismed.v102i11.4493\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tunisie Medicale","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.62438/tunismed.v102i11.4493","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Status Epilepticus in Children: Risk Factors and Clinical Evaluation.
Introduction and aim: Status epilepticus (SE) in children is a critical condition that can be life-threatening. The objective of this study was to identify factors associated with the occurrence of SE after a first convulsive seizure in children.
Methods: A retrospective study was conducted at the pediatric department of BEN AROUS regional hospital between January 2015 and December 2019.
Results: A total of 300 patients admitted for a first epileptic seizure were included in this analysis. The mean age of the patients was 33 months. Seizures were generalized in 92.7%, with tonic-clonic seizures being the most common (54.8%). SE was diagnosed as inaugural in 29% of cases. Abnormalities in EEG were observed in 36.5% of cases, while MRI revealed abnormal results in 32.8% of patients. Factors associated with a risk of SE recurrence were age younger than 1 year (p = 0.003), neuromotor retardation (p = 0.001), EEG abnormalities (p < 0.001), MRI abnormalities (p = 0.001), and abrupte discontinuation of antiepileptic treatment (p < 0.001). Simple febrile seizure was identified as a protective factor (p = 0.038).
Conclusion: The study identified that age under 1 year, neuromotor delay, and abnormalities in EEG and MRI are significant risk factors for the recurrence of status epilepticus after a first epileptic seizure in children. These findings suggest targeted preventive strategies to improve the management and prognosis of these patients.