[脑膜炎奈瑟菌引起的巴氏腺炎:临床病例]。

IF 1.8 4区 生物学 Q4 MICROBIOLOGY Revista Argentina de microbiologia Pub Date : 2024-11-19 DOI:10.1016/j.ram.2024.10.004
Elena Berardinelli, Marcela Sokol, Laura Dufranc, Vanina Diaz, Viviana Eiras, Ariel Giancieni, Patricia Galarza, Paula Gagetti, Federico Lorenzo, Adriana Efron
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引用次数: 0

摘要

巴氏腺炎是指巴氏腺导管内粘液积聚导致的炎症和感染,最常见的致病微生物是厌氧菌、需氧菌和性传播感染的病原体。由不属于生殖器微生物群的病原体引起的病例较少。同样,大多数情况下也是通过临床诊断。在此,我们描述了一名 42 岁异性恋女性的病例,她的巴氏腺脓肿是由脑膜炎奈瑟菌引起的,通过培养分离并经 VITEK®2 鉴定。在分子特征和亚型鉴定方面,采用多位点序列分型技术确定了序列类型和克隆复合体。通过对 PorA、fHbp、NHBA 和 NadA 的编码基因进行扩增和测序,研究了抗原谱,并通过 MIC 评估了药敏谱。通过分子诊断,确认脑膜炎双球菌是引起巴氏脑炎的病原体。
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[Bartholinitis due to Neisseria meningitidis: Clinical case].

Bartholinitis is the inflammation and infection of the Bartholin's glands that results from the accumulation of mucus in their ducts, the most frequent causal microorganisms being anaerobic and aerobic bacteria and those responsible for sexually transmitted infections. Those caused by agents not belonging to the genital microbiota are less frequent. Likewise, in most cases the diagnosis is clinical. Here, we describe the case of a 42-year-old heterosexual woman with a Bartholin's gland abscess caused by Neisseria meningitidis, isolated through culture and identified by VITEK®2. For molecular characterization and subtyping, the sequence type and clonal complex were determined using the multiple locus sequence typing technique. The antigenic profile was studied by amplification and sequencing of the genes coding for PorA, fHbp, NHBA and NadA and the susceptibility profile was assessed by MIC. Molecular diagnosis led to the confirmation of N. meningitidis as the pathogen responsible for bartholinitis.

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来源期刊
CiteScore
3.30
自引率
0.00%
发文量
46
审稿时长
>12 weeks
期刊介绍: La Revista Argentina de Microbiología es una publicación trimestral editada por la Asociación Argentina de Microbiología y destinada a la difusión de trabajos científicos en las distintas áreas de la Microbiología. La Asociación Argentina de Microbiología se reserva los derechos de propiedad y reproducción del material aceptado y publicado.
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