[无额外切除因素的 EMR 4 年后 pT1a 直肠癌复发病例]。

Q4 Medicine Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-10-01
Ayaka Fukui, Sho Sawazaki, Kiyoko Shimada, Masaki Takahashi, Yu Fujii, Hiroya Matabe, Tatsuya Kanai, Naohiko Matsushita, Mihwa Ju, Taiichi Kawabe, Hiroshi Tamagawa, Akio Higuchi, Keisuke Kazama, Toru Aoyama, Norio Yukawa, Naomi Kawano, Aya Saito, Hiroyuki Saeki
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引用次数: 0

摘要

一名 66 岁的男子因直肠乙状结肠(RS)部位长了一个息肉而接受了内镜粘膜切除术(EMR)。病理检查结果为:tub1、T1a、ly0、v0、HM0 和 VM0,没有任何需要额外治疗的因素。EMR 术后四年,造影剂增强 CT 扫描发现 252 号淋巴结区域有一个肿大的淋巴结呈造影剂增强。患者被诊断为癌症复发,并接受了腹腔镜高位前切除术和 D3 切除术。患者术后恢复良好,于术后第七天出院。病理诊断为直肠癌复发,特点是肿瘤外结节,未累及淋巴结结构。患者接受了四个疗程的 CAPOX 辅助化疗,术后两年零六个月未见复发。内镜下切除的 pT1a 直肠癌未考虑其他治疗因素的复发率相对较高,为 6.3%。因此,我们认为对患者进行密切随访非常重要。
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[A Case of Recurrence of pT1a Rectal Cancer after 4 Years of EMR without Additional Resection Factors].

A 66-year-old man underwent endoscopic mucosal resection(EMR)for a polyp located in the rectosigmoid(RS)region. The pathological findings was tub1, T1a, ly0, v0, HM0 and VM0, and there were no factors indicating the need for additional treatment. Four years following the EMR procedure, a contrast-enhanced CT scan revealed an enlarged lymph node exhibiting contrast enhancement in the area of #252 lymph nodes. The patient was diagnosed with recurrent cancer, and laparoscopic high anterior resection with D3 dissection was performed. The patient had a good postoperative course and was discharged from the hospital on the seventh day after the surgery. The pathological diagnosis was a recurrence of rectal cancer characterized by an extramural tumor nodule without involvement of lymph node structures. Four courses of CAPOX were administered as adjuvant chemotherapy, and there has been no recurrence observed 2 years and 6 months after the surgery. The recurrence rate for endoscopically resected pT1a rectal cancer with no additional treatment considerations is relatively high, at 6.3%. Therefore, we consider that it is important to follow up the patient closely.

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