通过生物电阻抗分析对新诊断为桥本氏甲状腺炎的甲状腺功能正常儿童进行身体成分评估。

IF 1.3 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Journal of Pediatric Endocrinology & Metabolism Pub Date : 2024-11-22 DOI:10.1515/jpem-2024-0420
Serkan Bilge Koca, Tarik Kirkgoz, Leyla Kara
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引用次数: 0

摘要

目的:甲状腺激素对身体成分的影响众所周知。我们的目的是在桥本氏甲状腺炎(HT)患儿和非桥本氏甲状腺炎患儿处于甲状腺功能正常时,通过生物电阻抗分析(BIA)检查他们的身体成分:研究对象包括年龄在 5 至 18 岁之间的 65 名桥本氏甲状腺炎患儿和 65 名健康儿童,每组各有 53 名女孩和 12 名男孩。使用 Tanita MC-780 MA 模型评估身体成分参数。这些参数包括脂肪量(FM)、无脂肪量(FFM)、肌肉量(MM)、骨量(BM)、身体总水分(TBW)、相位角、肌肉量与脂肪量的比率(MFR)、基础代谢率(BMR)和肌肉松弛指数(SI)。此外,还对体重、身高、体质指数标准偏差分值(SDS)和青春期状况进行了检测。此外,还比较了促甲状腺激素(TSH)、游离T4、游离T3、抗TPO、抗Tg、血清脂质水平和甲状腺体积:我们观察到,高密度脂蛋白血症组的总体重(27.5 ± 7.5 kg vs. 24.8 ± 6.6 kg; p=0.029)和基础代谢率(1,403 ± 253 kcal vs. 1,324 ± 200 kcal; p=0.049)更高。这些差异是由于男性组在年龄和肌肉质量上的差异造成的。通过 BIA 方法,甲状腺功能正常儿童的 FM、FFM、MM、BM、MFR、SI 和相位角得分在有 HT 和无 HT 的女性之间没有差异:结论:甲状腺功能正常的女性患者在入院时身体成分没有明显变化。
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Body composition assessment measured via bioelectrical impedance analysis in euthyroid children with newly diagnosed Hashimoto's thyroiditis.

Objectives: The effects of thyroid hormones on body composition are well-known. We aimed to examine the body composition of children with and without Hashimoto's thyroiditis (HT) by bioelectrical impedance analysis (BIA) while they were still euthyroid.

Methods: Between the ages of 5 and 18, 53 girls and 12 boys in each group, 65 children with HT, and 65 healthy children were included in this study. The Tanita MC-780 MA model was used to evaluate body composition parameters. These are fat mass (FM), fat-free mass (FFM), muscle mass (MM), bone mass (BM), total body water (TBW), phase angle, the ratio of muscle mass to fat mass (MFR), basal metabolic rate (BMR), and sarcopenic index (SI). Weight, height, body mass index standard deviation scores (SDSs), and pubertal status were examined. Additionally, TSH, Free-T4, Free-T3, Anti-TPO, Anti-Tg, serum lipid levels, and thyroid volumes were compared.

Results: We observed that TBW (27.5 ± 7.5 kg vs. 24.8 ± 6.6 kg; p=0.029) and BMR (1,403 ± 253 kcal vs. 1,324 ± 200 kcal; p=0.049) were higher in the HT group. These differences are due to differences in age and muscle mass in the male group. The FM, FFM, MM, BM, MFR, SI, and phase angle scores did not differ between females with and without HT in euthyroid children by the BIA method.

Conclusions: There is no significant change in body composition in euthyroid females with HT at admission.

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来源期刊
CiteScore
2.70
自引率
7.10%
发文量
176
审稿时长
3-6 weeks
期刊介绍: The aim of the Journal of Pediatric Endocrinology and Metabolism (JPEM) is to diffuse speedily new medical information by publishing clinical investigations in pediatric endocrinology and basic research from all over the world. JPEM is the only international journal dedicated exclusively to endocrinology in the neonatal, pediatric and adolescent age groups. JPEM is a high-quality journal dedicated to pediatric endocrinology in its broadest sense, which is needed at this time of rapid expansion of the field of endocrinology. JPEM publishes Reviews, Original Research, Case Reports, Short Communications and Letters to the Editor (including comments on published papers),. JPEM publishes supplements of proceedings and abstracts of pediatric endocrinology and diabetes society meetings.
期刊最新文献
CRH receptor antagonist crinecerfont - a promising new treatment option for patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Psychological and behavioral assessments in girls with idiopathic central precocious puberty. A novel de novo missense OTC mutation in an Iranian girl: a case report. High yield of congenital hypothyroidism among infants attending Children Hospital, Nairobi, Kenya. Facility based study in the absence of newborn screening. Body composition assessment measured via bioelectrical impedance analysis in euthyroid children with newly diagnosed Hashimoto's thyroiditis.
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