Dan Shao , Tingting Yu , Lianglong Sun , Zongfei Sun , Xiaorui Zhou , Chunyang Liu , Xuebo Chen , Xin Wang , Kai Sun
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Visible-light-induced three component difluoromethylation cyclization carbo-thioesterification to CF2-Containing γ-Lactams
A facile visible-light-induced photocatalytic cascade difluoromethylation cyclization of bromodifluoroacetamides and subsequent carbo-thioesterification is described. This protocol allows efficient access to a variety of valuable CF2-containing γ-lactams in moderate to excellent yields under mild conditions. Detailed mechanism study suggest that a radical pathway is involved in the catalytic cycle.
期刊介绍：
Molecular Catalysis publishes full papers that are original, rigorous, and scholarly contributions examining the molecular and atomic aspects of catalytic activation and reaction mechanisms. The fields covered are:
Heterogeneous catalysis including immobilized molecular catalysts
Homogeneous catalysis including organocatalysis, organometallic catalysis and biocatalysis
Photo- and electrochemistry
Theoretical aspects of catalysis analyzed by computational methods
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