Dan Shao , Tingting Yu , Lianglong Sun , Zongfei Sun , Xiaorui Zhou , Chunyang Liu , Xuebo Chen , Xin Wang , Kai Sun
{"title":"可见光诱导三组分二氟甲基化环化羧基硫代酯化生成含 CF2 的 γ-内酰胺","authors":"Dan Shao , Tingting Yu , Lianglong Sun , Zongfei Sun , Xiaorui Zhou , Chunyang Liu , Xuebo Chen , Xin Wang , Kai Sun","doi":"10.1016/j.mcat.2024.114685","DOIUrl":null,"url":null,"abstract":"<div><div>A facile visible-light-induced photocatalytic cascade difluoromethylation cyclization of bromodifluoroacetamides and subsequent carbo-thioesterification is described. This protocol allows efficient access to a variety of valuable CF<sub>2</sub>-containing <em>γ</em>-lactams in moderate to excellent yields under mild conditions. Detailed mechanism study suggest that a radical pathway is involved in the catalytic cycle.</div></div>","PeriodicalId":393,"journal":{"name":"Molecular Catalysis","volume":"570 ","pages":"Article 114685"},"PeriodicalIF":3.9000,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Visible-light-induced three component difluoromethylation cyclization carbo-thioesterification to CF2-Containing γ-Lactams\",\"authors\":\"Dan Shao , Tingting Yu , Lianglong Sun , Zongfei Sun , Xiaorui Zhou , Chunyang Liu , Xuebo Chen , Xin Wang , Kai Sun\",\"doi\":\"10.1016/j.mcat.2024.114685\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A facile visible-light-induced photocatalytic cascade difluoromethylation cyclization of bromodifluoroacetamides and subsequent carbo-thioesterification is described. This protocol allows efficient access to a variety of valuable CF<sub>2</sub>-containing <em>γ</em>-lactams in moderate to excellent yields under mild conditions. Detailed mechanism study suggest that a radical pathway is involved in the catalytic cycle.</div></div>\",\"PeriodicalId\":393,\"journal\":{\"name\":\"Molecular Catalysis\",\"volume\":\"570 \",\"pages\":\"Article 114685\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2024-11-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Catalysis\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2468823124008678\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Catalysis","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468823124008678","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Visible-light-induced three component difluoromethylation cyclization carbo-thioesterification to CF2-Containing γ-Lactams
A facile visible-light-induced photocatalytic cascade difluoromethylation cyclization of bromodifluoroacetamides and subsequent carbo-thioesterification is described. This protocol allows efficient access to a variety of valuable CF2-containing γ-lactams in moderate to excellent yields under mild conditions. Detailed mechanism study suggest that a radical pathway is involved in the catalytic cycle.
期刊介绍：
Molecular Catalysis publishes full papers that are original, rigorous, and scholarly contributions examining the molecular and atomic aspects of catalytic activation and reaction mechanisms. The fields covered are:
Heterogeneous catalysis including immobilized molecular catalysts
Homogeneous catalysis including organocatalysis, organometallic catalysis and biocatalysis
Photo- and electrochemistry
Theoretical aspects of catalysis analyzed by computational methods
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
