一名 11 岁儿童的结肠信号细胞癌:病例报告和文献综述

Pragya Singh , Lekshmi R , Sweety Gupta , Ravi Roushan Kumar , Shreyosi Mandal , Mridul Khanna , Satya Sree Balija , Ravi Hari Phulware , Manoj Gupta
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引用次数: 0

摘要

背景结肠癌在儿童中并不常见。本文报告了一例因急性肠梗阻就诊的 11 岁儿童罹患印戒细胞癌的病例。该患儿在直立位接受了腹部 X 光检查,结果显示肠套叠扩张。腹部对比增强计算机断层扫描显示,中横结肠周缘增厚,涉及 3.5 厘米。患儿接受了探查性开腹手术,术中发现了中横结肠肿瘤。肿瘤切除后进行了侧对侧吻合术。术后组织病理学检查显示为标志环细胞癌。结论手术后辅助化疗是治疗结直肠癌的方式。目前还没有针对儿童年龄组的筛查指南,但可以考虑通过结肠镜筛查进行早期诊断,以改善预后。
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Signet cell carcinoma of the colon in an 11-year-old child: A case report and review of literature

Background

Colon cancer is uncommon in children. This article reports a case of signet ring cell carcinoma in an 11-year-old child who presented with acute intestinal obstruction.

Case report

An 11-year-old boy presented with progressive abdominal distension associated with constipation. The child underwent an abdominal X-ray in the erect position which revealed dilated bowel loops. Contrast enhanced computed tomography abdomen reported circumferential thickening involving 3.5 cm of the mid-transverse colon. The child underwent exploratory laparotomy which revealed mid transverse colon tumor. Tumor was resected with side-to-side anastomosis. Postoperative histopathology showed signet ring cell carcinoma. He was started on adjuvant chemotherapy.

Conclusion

Surgery followed by adjuvant chemotherapy is the modality of treatment colorectal carcinoma. There are no screening guidelines available for the pediatric age group, however early diagnosis through colonoscopy screening can be considered to improve the prognosis.
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