Nicoletta Cantarutti, Rachele Adorisio, Sara Di Marzio, Marianna Cicenia, Irma Battipaglia, Erica Mencarelli, Massimo Stefano Silvetti, Antonio Amodeo, Fabrizio Drago
{"title":"Nt-Pro-Bnp 在预测小儿肥厚型心肌病预后中的作用。","authors":"Nicoletta Cantarutti, Rachele Adorisio, Sara Di Marzio, Marianna Cicenia, Irma Battipaglia, Erica Mencarelli, Massimo Stefano Silvetti, Antonio Amodeo, Fabrizio Drago","doi":"10.1007/s00246-024-03702-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Hypothesis: </strong>The aim of the study was to evaluate the correlation between NTproBNP and left ventricular mass (LVM) in children affected by hypertrophic cardiomyopathy (HCM), both asymptomatic, symptomatic, and with implantable cardioverter-defibrillator (ICD).</p><p><strong>Methods: </strong>A total of 225 pediatric patients were evaluated and 45 were enrolled in the study because met inclusion criteria (age < 18 years; diagnosis of hypertrophic cardiomyopathy; NTproBNP > 600 pg/ml).</p><p><strong>Results: </strong>The analysis showed a significant correlation between NTproBNP level and LVM (p = 0.024). ANOVA test showed that high level of NTproBNP and LVM were significantly correlated to ICD implantation (p = 0.001; p = 0.003). Multivariate analysis showed NTproBNP as an independent risk factor for ICD implantation (p = 0.035).</p><p><strong>Conclusion: </strong>Our study showed that NTproBNP levels directly correlated to LVM and disease progression and it was found to be predictive, together with LVM, of ICD implantation.</p>","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Role of Nt-Pro-Bnp in Predicting Outcome in Pediatric Hypertrophic Cardiomyopathy.\",\"authors\":\"Nicoletta Cantarutti, Rachele Adorisio, Sara Di Marzio, Marianna Cicenia, Irma Battipaglia, Erica Mencarelli, Massimo Stefano Silvetti, Antonio Amodeo, Fabrizio Drago\",\"doi\":\"10.1007/s00246-024-03702-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Hypothesis: </strong>The aim of the study was to evaluate the correlation between NTproBNP and left ventricular mass (LVM) in children affected by hypertrophic cardiomyopathy (HCM), both asymptomatic, symptomatic, and with implantable cardioverter-defibrillator (ICD).</p><p><strong>Methods: </strong>A total of 225 pediatric patients were evaluated and 45 were enrolled in the study because met inclusion criteria (age < 18 years; diagnosis of hypertrophic cardiomyopathy; NTproBNP > 600 pg/ml).</p><p><strong>Results: </strong>The analysis showed a significant correlation between NTproBNP level and LVM (p = 0.024). ANOVA test showed that high level of NTproBNP and LVM were significantly correlated to ICD implantation (p = 0.001; p = 0.003). Multivariate analysis showed NTproBNP as an independent risk factor for ICD implantation (p = 0.035).</p><p><strong>Conclusion: </strong>Our study showed that NTproBNP levels directly correlated to LVM and disease progression and it was found to be predictive, together with LVM, of ICD implantation.</p>\",\"PeriodicalId\":19814,\"journal\":{\"name\":\"Pediatric Cardiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-11-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pediatric Cardiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00246-024-03702-7\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00246-024-03702-7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
The Role of Nt-Pro-Bnp in Predicting Outcome in Pediatric Hypertrophic Cardiomyopathy.
Hypothesis: The aim of the study was to evaluate the correlation between NTproBNP and left ventricular mass (LVM) in children affected by hypertrophic cardiomyopathy (HCM), both asymptomatic, symptomatic, and with implantable cardioverter-defibrillator (ICD).
Methods: A total of 225 pediatric patients were evaluated and 45 were enrolled in the study because met inclusion criteria (age < 18 years; diagnosis of hypertrophic cardiomyopathy; NTproBNP > 600 pg/ml).
Results: The analysis showed a significant correlation between NTproBNP level and LVM (p = 0.024). ANOVA test showed that high level of NTproBNP and LVM were significantly correlated to ICD implantation (p = 0.001; p = 0.003). Multivariate analysis showed NTproBNP as an independent risk factor for ICD implantation (p = 0.035).
Conclusion: Our study showed that NTproBNP levels directly correlated to LVM and disease progression and it was found to be predictive, together with LVM, of ICD implantation.
期刊介绍：
The editor of Pediatric Cardiology welcomes original manuscripts concerning all aspects of heart disease in infants, children, and adolescents, including embryology and anatomy, physiology and pharmacology, biochemistry, pathology, genetics, radiology, clinical aspects, investigative cardiology, electrophysiology and echocardiography, and cardiac surgery. Articles which may include original articles, review articles, letters to the editor etc., must be written in English and must be submitted solely to Pediatric Cardiology.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
