用于可穿戴设备的缝合式纺织品微流体。

IF 6.1 2区 工程技术 Q1 BIOCHEMICAL RESEARCH METHODS Lab on a Chip Pub Date : 2024-11-27 DOI:10.1039/d4lc00697f
Martin Hanze, Andrew Piper, Mahiar Max Hamedi
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引用次数: 0

摘要

基于线的微流控技术依靠线中的毛细力实现液体流动,是传统微流控技术的一种很有前途的替代技术,因为这种技术可以很容易地集成到基于纺织品的可穿戴生物传感器中。我们在此介绍通过机器缝合制造的先进纺织品微流控装置,这些装置仅使用市场上可买到的纺织品。我们将具有增强排汗能力的涤纶 "Coolmax®"纱线缝合到疏水性织物和疏水性处理过的可伸缩织物中,这些织物可作为非排汗基质。这样,我们构建的纺织品微流体能够实现多种功能,包括二维和三维配置中的混合和分离。此外,我们还将缝合的微流体装置集成到可穿戴的 T 恤衫中,并展示了这种装置可以收集、传输和检测穿戴者皮肤上的汗液。这些设备还可以机洗,因此本身就可以重复使用。最后,我们将电化学传感器集成到基于纺织品的微流控装置中,使用缝合的金涂层纱线来检测微流控纱线中的分析物。我们的缝合纺织品微流控装置有望用于可穿戴诊断应用。这种新颖的自下而上的机器缝合制造方法具有可扩展性、可重复性、低成本,并且与现有的纺织制造业兼容。
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Stitched textile-based microfluidics for wearable devices.

Thread-based microfluidics, which rely on capillary forces in threads for liquid flow, are a promising alternative to conventional microfluidics, as they can be easily integrated into wearable textile-based biosensors. We present here advanced textile-based microfluidic devices fabricated by machine stitching, using only commercially available textiles. We stitch a polyester "Coolmax®" yarn with enhanced wicking abilities into both hydrophobic fabric and hydrophobically treated stretchable fabric, that serve as non-wicking substrates. In doing so we construct textile microfluidics capable of performing a wide variety of functions, including mixing and separation in 2D and 3D configurations. Furthermore, we integrate a stitched microfluidic device into a wearable T-shirt and show that this device can collect, transport, and detect sweat from the wearer's skin. These can also be machine-washed, making them inherently reusable. Finally, we integrate electrochemical sensors into the textile-based microfluidic devices using stitched gold-coated yarns to detect analytes in the microfluidic yarns. Our stitched textile-based microfluidic devices hold promise for wearable diagnostic applications. This novel, bottom-up fabrication using machine stitching is scalable, reproducible, low-cost, and compatible with the existing textile manufacturing industry.

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来源期刊
Lab on a Chip
Lab on a Chip 工程技术-化学综合
CiteScore
11.10
自引率
8.20%
发文量
434
审稿时长
2.6 months
期刊介绍: Lab on a Chip is the premiere journal that publishes cutting-edge research in the field of miniaturization. By their very nature, microfluidic/nanofluidic/miniaturized systems are at the intersection of disciplines, spanning fundamental research to high-end application, which is reflected by the broad readership of the journal. Lab on a Chip publishes two types of papers on original research: full-length research papers and communications. Papers should demonstrate innovations, which can come from technical advancements or applications addressing pressing needs in globally important areas. The journal also publishes Comments, Reviews, and Perspectives.
期刊最新文献
A gravity-driven microfluidic metering system for automation of multiplexed bioassays. Advancing cellular transfer printing: achieving bioadhesion-free deposition via vibration microstreaming. Correction: Distal renal tubular system-on-a-chip for studying the pathogenesis of influenza A virus-induced kidney injury. Rapid automated production of tubular 3D intestine-on-a-chip with diverse cell types using coaxial bioprinting. An integrated microfluidic device for sorting of tumor organoids using image recognition.
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